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[Capping strategies in RNA viruses].
Medecine sciences : M/S, 2012Most viruses use the mRNA-cap dependent cellular translation machinery to translate their mRNAs into proteins. The addition of a cap structure at the 5' end of mRNA is therefore an essential step for the replication of many virus families. Additionally, the cap protects the viral RNA from degradation by cellular nucleases and prevents viral RNA ...
Mickaël, Bouvet +7 more
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Priming of Influenza Viral RNA Transcription by Capped Heterologous RNAs
1981Influenza virus is a negative-stranded RNA virus, i.e., the viral messenger RNA (mRNA) is complementary to the genome RNA (which is segmented), and the virion contains the enzyme system which transcribes the genome RNA into the viral mRNA. This virus employs a unique mechanism for the initiation of the synthesis of its mRNA.
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Synthesis of RNA having cap structure.
Nucleic acids symposium series, 1991RNA consisting 43 nucleotides bearing cap structure was synthesized (Figure). In the first place, 9 mer of a leader sequence with the cap structure (F-1) was synthesized by the phosphotriester method and followed by the capping reaction. Next, 32 mer of a cistron was divided into two fragments and each was synthesized by the phosphoramidite method. The
R, Iwase +5 more
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Cellular functions of eukaryotic RNA helicases and their links to human diseases
Nature Reviews Molecular Cell Biology, 2023Katherine E Bohnsack +2 more
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RNA contributions to the form and function of biomolecular condensates
Nature Reviews Molecular Cell Biology, 2020Amy S Gladfelter
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A brave new world of RNA-binding proteins
Nature Reviews Molecular Cell Biology, 2018Matthias W Hentze +2 more
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