Results 191 to 200 of about 1,834,577 (295)

Structural insights into RNA cleavage by a novel family of bacterial RNases. [PDF]

Nucleic Acids Res
Wu R, Ingle S, Barnes SA, Dahlin HR, Khamrui S, Xiang Y, Shi Y, Bechhofer DH, Lazarus MB.   +8 more
europepmc   +1 more source

PRMT1 methylates the single Argonaute of Toxoplasma gondii and is important for the recruitment of Tudor nuclease for target RNA cleavage by antisense guide RNA

Cellular Microbiology, 2012
A. Musiyenko, T. Majumdar, J. Andrews, B. Adams, S. Barik   +4 more
semanticscholar   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Strict conformational demands of RNA cleavage in bulge-loops created by peptidyl-oligonucleotide conjugates. [PDF]

Nucleic Acids Res, 2020
Staroseletz Y, Amirloo B, Williams A, Lomzov A, Burusco KK, Clarke DJ, Brown T, Zenkova MA, Bichenkova EV.   +8 more
europepmc   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Evaluation of the effect of RNA secondary structure on Cas13d-mediated target RNA cleavage. [PDF]

Mol Ther Nucleic Acids
Hussein M, Liu Y, Vink M, Kroon PZ, Das AT, Berkhout B, Herrera-Carrillo E.   +6 more
europepmc   +1 more source

DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks. [PDF]

Cell Rep, 2020
Saha S, Sun Y, Huang SN, Baechler SA, Pongor LS, Agama K, Jo U, Zhang H, Tse-Dinh YC, Pommier Y.   +9 more
europepmc   +1 more source

Ultrasound‐Responsive Dual‐Prodrug Nanoassembly for “Fenestrae‐Restoration Strategy” in Liver Fibrosis Therapy

Advanced Materials, EarlyView.
ABSTRACT Liver fibrosis is a serious yet reversible intermediate stage in the progression of liver disease, which can ultimately advance to cirrhosis and hepatocellular carcinoma. Targeted and selective inhibition of activated hepatic stellate cells (aHSCs) has emerged as a promising therapeutic strategy for the treatment of liver fibrosis.
Shutong Liu, Mengyao Zhang, Zitong Qiu, Xinyi Liu, Yunsheng Dou, Sona Krizkova, Zheyi Li, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response. [PDF]

Cell Rep
Karasik A, Lorenzi HA, DePass AV, Guydosh NR.   +3 more
europepmc   +1 more source

Surface‐Capped Protein Nanoparticles for Nonviral Gene Delivery

Advanced Materials, EarlyView.
ABSTRACT Developing simple, safe, and efficient nonviral delivery systems remains a significant challenge in bioengineering. Nanoparticles offer promising gene delivery capabilities with reduced toxicity; however, long‐standing challenges related to effective plasmid encapsulation and delivery exist.
Fjorela Xhyliu, Yao Yao, Yeongun Ko, Grant Grasman, Jeffery E. Raymond, Albert Chang, Yuxuan Deng, Grant Dominic, Michael Triebwasser, Joerg Lahann   +9 more
wiley   +1 more source