Results 171 to 180 of about 208,041 (335)

The nucleolus is the site for inflammatory RNA decay during infection. [PDF]

open access: yesNat Commun, 2022
Lee TA   +18 more
europepmc   +1 more source

Quantitation of RNA decay in dried blood spots during 20 years of storage [PDF]

open access: green, 2009
Fredrika Gauffin   +4 more
openalex   +1 more source

GbSER02 Interacts With GhVOZ1 to Promote Fiber Elongation by Modulating Gibberellin Synthesis in Cotton

open access: yesAdvanced Science, EarlyView.
GbSER02 with a single base change (SNP517G) encodes normal serpin protein and interacts with transcription factor VOZ1 to alleviate the repression of VOZ1 on GA3ox1 and promote GA3 biosynthesis. Further, GA3 induces the expression of cell wall loosening‐related genes and decreases flavonoid content, ultimately facilitating fiber cell elongation in ...
Hao Jia   +12 more
wiley   +1 more source

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl- l -carnitine and/or R -α-lipoic acid

open access: green, 2002
Jiankang Liu   +7 more
openalex   +1 more source

Carrier‐Free Nanocapsule with Dual‐Target Capacity for Synergistically Restoring Inflammatory Microenvironment and Microbiota Dysbiosis in Colitis

open access: yesAdvanced Science, EarlyView.
This manuscript presents a carrier‐free nanomedicine PCNPs@PEG‐Man with dual‐targeting for IBD. It resists harsh intestinal conditions, reduces oxidative stress, enhances drug uptake and retention, modulates inflammation, and reshapes gut microbiota, offering a safe and effective IBD therapy.
Yingjie Chen   +8 more
wiley   +1 more source

Compromised nonsense-mediated RNA decay results in truncated RNA-binding protein production upon DUX4 expression. [PDF]

open access: yesCell Rep, 2023
Campbell AE   +12 more
europepmc   +1 more source

PTf‐SRiApt Targeting SCAF4‐POLR2A Interaction Suppresses Tumor Growth and Promotes Antitumor Immunity in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
A phosphorothioate‐modified aptamer PTf‐SRiApt capable of disrupting “undruggable” transcription factor SCAF4‐POLR2A interaction with high inhibitory activity and biological stability is presented here. Through this inhibition, PTf‐SRiApt successfully arrested cell cycle progression, induced cell death, and elevated immune recruitment in SCAF4‐POLR2A ...
Liyan Fei   +13 more
wiley   +1 more source

Comparative analyses suggest a link between mRNA splicing, stability, and RNA covalent modifications in flowering plants

open access: yesBMC Plant Biology
Background In recent years, covalent modifications on RNA nucleotides have emerged as pivotal moieties influencing the structure, function, and regulatory processes of RNA Polymerase II transcripts such as mRNAs and lncRNAs. However, our understanding of
Kyle Palos   +4 more
doaj   +1 more source

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