Results 211 to 220 of about 962,124 (298)

A nuclear RNA degradation code is recognized by PAXT for eukaryotic transcriptome surveillance. [PDF]

Mol Cell
Soles LV, Liu L, Zou X, Yoon Y, Li S, Tian L, Valdez M, Yu AM, Yin H, Li W, Ding F, Seelig G, Li L, Shi Y.   +13 more
europepmc   +1 more source

The Floor‐Ceiling‐Chip, or 2 × 2D = Pseudo‐3D—Approaching 3D Cell Morphology and Organization between Two Opposing 2D Substrates with Cell‐Adhesive Protein Micropatterns

Advanced Healthcare Materials, EarlyView.
Here, we present a novel 3D cell patterning and culture platform. The “Floor‐Ceiling‐Chip” (FC‐Chip) consists of two opposing track‐etched membranes, creating a pseudo‐3D microenvironment for the cells in between. By providing the membranes with micropatterned cell‐adhesive islands of varying geometries and sizes, the FC‐Chip enables control over cell ...
Urandelger Tuvshindorj, Francesca Giacomini, Esra Güben Kaçmaz, Tim ten Brink, Lorenzo Moroni, Zeinab Tahmasebi Birgani, Clemens van Blitterswijk, Pamela Habibović, Stefan Giselbrecht, Jan de Boer, Roman Truckenmüller   +10 more
wiley   +1 more source

RIBOTACs – Targeted Degradation of RNA [PDF]

Synfacts, 2020
openaire   +1 more source

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

SUMOylated Senataxin functions in genome stability, RNA degradation, and stress granule disassembly, and is linked with inherited ataxia and motor neuron disease. [PDF]

Mol Genet Genomic Med, 2021
Bennett CL, La Spada AR.
europepmc   +1 more source

RNA degradation patterns in cardiac tissues kept at different time intervals and temperatures before RNA sequencing. [PDF]

PLoS One
Jacobsen SB, Tfelt-Hansen J, Smerup MH, Morling N, Andersen JD.   +4 more
europepmc   +1 more source

Apparent RNA bridging between PRC2 and chromatin is an artefact of non-specific chromatin precipitation upon RNA degradation

, 2023
Hickman AH, Jenner RG.
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

RNA degradation triggered by decapping is largely independent of initial deadenylation. [PDF]

EMBO J
Audebert L, Feuerbach F, Zedan M, Schürch AP, Decourty L, Namane A, Permal E, Weis K, Badis G, Saveanu C.   +9 more
europepmc   +1 more source

RNA degradation eliminates developmental transcripts during murine embryonic stem cell differentiation via CAPRIN1-XRN2.

Dev Cell, 2022
Viegas JO, Azad GK, Lv Y, Fishman L, Paltiel T, Pattabiraman S, Park JE, Kaganovich D, Sze SK, Rabani M, Esteban MA, Meshorer E.   +11 more
europepmc   +1 more source