Evolution of ribonuclease H genes in prokaryotes to avoid inheritance of redundant genes [PDF]
BMC Evolutionary Biology, 2007 Background A theoretical model of genetic redundancy has proposed that the fates of redundant genes depend on the degree of functional redundancy, and that functionally redundant genes will not be inherited together.
Tomita Masaru +2 more
doaj +4 more sources
PRRSV Nsp11 antagonizes host antiviral immune response by reducing OAS1 and RNase L expressions [PDF]
BMC Veterinary ResearchBackground Porcine reproductive and respiratory syndrome virus (PRRSV) is the pathogen of porcine reproductive and respiratory syndrome (PRRS) which is an important viral infectious disease.
Dandan Jiang +11 more
doaj +2 more sources
Bacterial Biodiversity of the Kapova Karst Cave as a Source of Hydrolases Producers
European Journal of Biology, 2023 Objective: Recent studies have revealed the biodiversity of both cultivated and uncultivated microbiomes in extreme environments. It has been shown that terrestrial subsurface ecosystems contain vast metabolic potential.
Willam Kurdy +2 more
doaj +1 more source
Evaluation of Ribonuclease (RNAse) Activity in the Sera of Women with Breast Tumor. [PDF]
Kirkuk Journal of Science, 2019 In this study 125 patients with breast tumors (61 patients with benign breast tumors, 64 patients with malignant breast tumors) with age range between (20-75) years collected from Center of Early Detection of Breast Cancer in Azady Teaching Hospital in ...
Basma Tawfeq, Kdiar Kdiar, Sabah Kurshid
doaj +1 more source
Enzymatic activity necessary to restore the lethality due to Escherichia coli RNase E deficiency is distributed among bacteria lacking RNase E homologues. [PDF]
PLoS ONE, 2017 Escherichia coli RNase E (Eco-RNase E), encoded by rne (Eco-rne), is considered the global RNA decay initiator. Although Eco-RNase E is an essential gene product in E.
Masaru Tamura +4 more
doaj +1 more source
Divalent metal ion-induced folding mechanism of RNase H1 from extreme halophilic archaeon Halobacterium sp. NRC-1. [PDF]
PLoS ONE, 2014 RNase H1 from Halobacterium sp. NRC-1 (Halo-RNase H1) is characterized by the abundance of acidic residues on the surface, including bi/quad-aspartate site residues.
Elias Tannous, Shigenori Kanaya
doaj +1 more source
Human RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processing. [PDF]
PLoS ONE, 2013 Mammalian RNase H1 has been implicated in mitochondrial DNA replication and RNA processing and is required for embryonic development. We identified the mitochondrial protein P32 that binds specifically to human RNase H1, but not human RNase H2. P32 binds
Hongjiang Wu +4 more
doaj +1 more source
RNase HI Is Essential for Survival of Mycobacterium smegmatis [PDF]
, 2015 RNases H are involved in the removal of RNA from RNA/DNA hybrids. Type I RNases H are thought to recognize and cleave the RNA/DNA duplex when at least four ribonucleotides are present.
Brzostek, Anna M. +7 more
core +9 more sources
Evasion of antiviral innate immunity by Theiler's virus L* protein through direct inhibition of RNase L. [PDF]
PLoS Pathogens, 2013 Theiler's virus is a neurotropic picornavirus responsible for chronic infections of the central nervous system. The establishment of a persistent infection and the subsequent demyelinating disease triggered by the virus depend on the expression of L*, a ...
Frédéric Sorgeloos +3 more
doaj +1 more source
Cell Insight, 2023 R-loops are regulators of many cellular processes and are threats to genome integrity. Therefore, understanding the mechanisms underlying the regulation of R-loops is important.
Le Li +9 more
doaj +1 more source