Three essential ribonucleases-RNase Y, J1, and III-control the abundance of a majority of Bacillus subtilis mRNAs. [PDF]
PLoS Genetics, 2012 Bacillus subtilis possesses three essential enzymes thought to be involved in mRNA decay to varying degrees, namely RNase Y, RNase J1, and RNase III. Using recently developed high-resolution tiling arrays, we examined the effect of depletion of each of ...
Sylvain Durand +4 more
doaj +1 more source
A functional RNase P protein subunit of bacterial origin in some eukaryotes [PDF]
, 2011 RNase P catalyzes 5′-maturation of tRNAs. While bacterial RNase P comprises an RNA catalyst and a protein cofactor, the eukaryotic (nuclear) variant contains an RNA and up to ten proteins, all unrelated to the bacterial protein.
Bernal Bayard, Pilar +5 more
core +1 more source
RNase A Promotes Proliferation of Neuronal Progenitor Cells via an ERK-Dependent Pathway
Frontiers in Molecular Neuroscience, 2018 Members of the ribonuclease A (RNase A) superfamily regulate various physiological processes. RNase A, the best-studied member of the RNase A superfamily, is widely expressed in different tissues, including brains.
Hsin-Yu Liu +9 more
doaj +1 more source
Inhibition of Murine Cytomegalovirus Infection in Animals by RNase P-Associated External Guide Sequences. [PDF]
, 2017 External guide sequence (EGS) RNAs are associated with ribonuclease P (RNase P), a tRNA processing enzyme, and represent promising agents for gene-targeting applications as they can direct RNase-P-mediated cleavage of a target mRNA.
Li, Wei +9 more
core +2 more sources
Control of expression of the RNases J1 and J2 in bacillus subtilis [PDF]
, 2014 In Bacillus subtilis, the dual activity 5' exo- and endoribonucleases J1 and J2 are important players in mRNA and stable RNA maturation and degradation. Recent work has improved our understanding of their structure and mechanism of action and identified ...
Hébert, A. +3 more
core +1 more source
Frontiers in Microbiology, 2019 Regulated RNA turnover is vital for the control of gene expression in all cellular life. In Escherichia coli, this process is largely controlled by a stable degradosome complex containing RNase E and a variety of additional enzymes.
Rong Mu +6 more
doaj +1 more source
Phosphatidic acid counteracts S-RNase signaling in pollen by stabilizing the actin cytoskeleton [PDF]
, 2018 S-RNase is the female determinant of self-incompatibility (SI) in pear (Pyrus bretschneideri). After translocation to the pollen tube, S-RNase degrades rRNA and induces pollen tube death in an S-haplotype-specific manner. In this study, we found that the
Chen, Jianqing +7 more
core +1 more source
RNase H1 and H2 Are Differentially Regulated to Process RNA-DNA Hybrids
Cell Reports, 2019 Summary: RNA-DNA hybrids are tightly regulated to ensure genome integrity. The RNase H enzymes RNase H1 and H2 contribute to chromosomal stability through the removal of RNA-DNA hybrids.
Arianna Lockhart +7 more
doaj +1 more source
Yeast RNase H(35) is the counterpart of the mammalian RNase HI, and is evolutionarily related to prokaryotic RNase HII1We dedicate this work to the memory of our colleague Robert Karwan (1959–1997).1 [PDF]
, 1934 We cloned the Saccharomyces cerevisiae homologue of mammalian RNase HI, which itself is related to the prokaryotic RNase HII, an enzyme of unknown function and previously described as having minor activity in Escherichia coli.
Frank, Peter +2 more
core +1 more source
The Antimicrobial and Immunomodulatory Function of RNase 7 in Skin
Frontiers in Immunology, 2019 The human ribonuclease RNase 7 has been originally isolated from human skin and is a member of the human RNase A superfamily. RNase 7 is constantly released by keratinocytes and accumulates on the skin surface.
Franziska Rademacher +7 more
doaj +1 more source