Results 161 to 170 of about 143,515 (300)

Browsing RNA Structures by Interactive Sonification

, 2010
Grond F, Janssen S, Schirmer S, Hermann T. Browsing RNA Structures by Interactive Sonification. In: Bresin R, Hermann T, Hunt A, eds. Proceedings of the 3rd Interactive Sonification Workshop.
Bresin, Roberto, Hermann, Thomas, Hunt, Andy, Schirmer, Stefanie, Janssen, Stefan ; https://orcid.org/, Grond, Florian, Hermann, Thomas ; https://orcid.org/   +6 more
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

XML schemas for common bioinformatic data types and their application in workflow systems

, 2006
Seibel PN, Krüger J, Hartmeier S, et al. XML schemas for common bioinformatic data types and their application in workflow systems. BMC Bioinformatics.
Krüger, Jan, Seibel Philipp N, Sven Hartmeier, Krüger Jan, Giegerich, R., Philipp N Seibel, Hartmeier Sven, Schwarzer Knut, Henning Mersch, Schwarzer, Knut, Seibel, Philipp N., Knut Schwarzer, Löwenthal Kai, Krüger, J., Dandekar, Th., Robert Giegerich, Giegerich, Robert, Jan Krüger, Dandekar, Thomas, Löwenthal, Kai, Mersch Henning, Hartmeier, S., Thomas Dandekar, Seibel, P. N., Krueger, Jan, Mersch, Henning, Löwenthal, K., Kai Löwenthal, Giegerich Robert, Schwarzer, K., Dandekar Thomas, Hartmeier, Sven, Mersch, H.   +32 more
core   +1 more source

Pervasive RNA folding is crucial for narnavirus genome maintenance. [PDF]

Proc Natl Acad Sci U S A, 2023
Fukuda M, Cai J, Bader JS, Boeke JD.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Investigation of the structure and dynamics of RNA systems by molecular dynamics simulations

, 2007
Das genetische Material der Zellen besteht aus Molekülketten der Desoxyribonukleinsäure (DNA), die ein Träger der Erbinformation ist. In normalen Körperzellen wird die Erbinformation der DNA in eine andere Molekülkette, die sogenannte Ribonukleinsäure ...
Widjajakusuma, Elisabeth Catherina
core  

RNA Folding [PDF]

Biophysical Journal, 2008
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source