The advances of DEAD-box RNA helicase 17 in chronic non-infectious diseases. [PDF]
Xiong M +8 more
europepmc +1 more source
This graphical abstract illustrates the complete translational pipeline of Terminalia arjuna in modern phytomedicine and functional food development. It is rich in key bioactive compounds like arjunolic acid, arjungenin, flavonoids, and tannins which serve as the foundation for the plant's versatile medicinal uses and offers broad therapeutic benefits ...
Ishani Banerjee +5 more
wiley +1 more source
Mitochondrial RNA helicase DDX28 promotes cell cycle and DNA repair programs and shapes an immunosuppressive microenvironment in acute myeloid leukemia. [PDF]
Wang Z, Liu Y, Guan X, Ye M, Xu X.
europepmc +1 more source
Two novel lytic Enterobacter phages, HHH and RZH, displayed targeted antibiofilm activity against MDR Enterobacter cloacae complex biofilms when combined with EDTA. Activity was strongest within a narrow low‐millimolar EDTA window, reducing biofilm biomass and viable burden, while higher EDTA concentrations shifted the interaction towards antagonism ...
Kashif Haq +4 more
wiley +1 more source
Correction: The multifunctional RNA helicase DDX39A drives glioblastoma progression by modulating WISP1 alternative splicing that induces an immunosuppressive macrophage polarization. [PDF]
Zhang Y +19 more
europepmc +1 more source
Epitranscriptomics is understudied in bacteria but has the ability to modulate antimicrobial resistance, virulence and pathogenicity. Pitt et al. implement two cutting‐edge techniques: CRISPR interference and Nanopore direct RNA sequencing along with functional assays to study RNA modifications in Escherichia coli.
Miranda E. Pitt +8 more
wiley +1 more source
Unwinding new therapeutic opportunities in rhabdomyosarcoma: the role of RNA helicase DDX5. [PDF]
Bianconi V, Mozzetta C.
europepmc +1 more source
Intrinsic Disorder as a New Frontier in Antimicrobial Resistance and Bacterial Fitness
The works examines the link between intrinsic disorder in bacterial protein structure, and bacterial function, and antimicrobial resistance. It highlights how flexible, disordered proteins support secretion, stress responses, desiccation protection, and virulence, while also suggesting that these adaptable regions may provide novel targets for ...
Jack O' Callaghan +3 more
wiley +1 more source
The conserved SEN1 DNA/RNA helicase has multiple functions during yeast meiosis. [PDF]
Gaglione R +6 more
europepmc +1 more source
Clinical and Molecular Features of BAP1‐Mutated Meningiomas: Case Series
ABSTRACT BRCA1‐associated protein 1 (BAP1)‐deficient meningiomas represent a clinically and molecularly distinct subgroup with variable histology and aggressive behavior that may not be fully captured by current grading criteria. The clinical spectrum of BAP1 alterations in meningiomas, including both somatic and germline contexts, remains incompletely
Ivan Pradilla +7 more
wiley +1 more source

