Results 171 to 180 of about 99,329 (307)
Transcript correlation analysis allowed the identification of several key nodes in the complex regulatory network of plant iron metabolism. Abstract Arabidopsis thaliana was the first plant genome to be fully sequenced, almost a quarter of a century ago, thanks to The Arabidopsis Genome Initiative, with contributions from scientists worldwide.
I. Murgia, P. Morandini
wiley +1 more source
Understanding exosomes in regenerative dentistry
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad +2 more
wiley +1 more source
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri +13 more
wiley +1 more source
Abstract Epigenetic markers, particularly DNA methylation, are promising tools for monitoring athlete health and training due to their role in cellular regulation, exercise responsiveness and molecular stability. However, exercise‐induced epigenetic changes in peripheral blood in trained individuals remain unexplored.
C. D. Goldsmith +6 more
wiley +1 more source
DDX21 Promotes Breast Cancer Growth and Metastasis via Stimulating RNAPII Elongation During Hypoxia
DDX21 triggers CDK9 release from the 7SK RNP complex. DDX21‐CDK9 binding to HIFs drives transcriptional reprogramming during hypoxia. DDX21 enhances breast cancer progression and metastasis. Elevated DDX21 expression correlates with poor prognosis in breast cancer patients.
Guangqiang Li +11 more
wiley +1 more source
Conserved RNA helicase Vasa regulates ribonucleoprotein condensate dynamics and mRNA localization. [PDF]
Tian S, Kim H, Curnutte HA, Trcek T.
europepmc +1 more source
RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment
Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li +3 more
wiley +1 more source
The RNA helicase eIF4A as a novel target in insect cells to combat arboviral infections. [PDF]
Rehling T +9 more
europepmc +1 more source
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni +5 more
wiley +1 more source

