Results 161 to 170 of about 125,618 (325)
Disruption of an RNA helicase/RNAse III gene in Arabidopsis causes unregulated cell division in floral meristems [PDF]
, 1999 Arabidopsis thaliana floral meristems are determinate structures that produce a defined number of organs, after which cell division ceases. A new recessive mutant, carpel factory (caf), converts the floral meristems to an indeterminate state.
Jacobsen, Steven E. +2 more
core
Cancer Science, EarlyView.We have uncovered a novel mechanism by which HROB modulates cell proliferation in lung adenocarcinoma. Our findings suggest that HROB recruits ZC3HC1 and mediates its de‐phosphorylation at Ser354, which in turn promotes K27‐linked ubiquitination of CCNB1, leading to its proteasomal degradation.
Zhe Zhang +12 more
wiley +1 more source
RNA Helicase A Mediates Association of CBP with RNA Polymerase II [PDF]
, 1997 Toshihiro Nakajima +6 more
openalex +1 more source
Purifikasi Inhibitor Atpase/rna Helikase Virus Japanese Encephalitis dari Streptomyces Chartreusis [PDF]
, 2009 Japanese encephalitis virus (JEV) is a neuropathogenic virus commonly caused cen-tral nervous diseases such as meningitis and severe encephalitis. Although vaccine has been developed, no specific and effective drug is available so far.
Elfita, L. (Lina) +4 more
core
A Novel UPF1 Variant Associated With a Rare UPF1‐Related Neurodevelopmental Disorder
Clinical Genetics, EarlyView.Nonsense‐mediated mRNA decay (NMD) plays a crucial role in degrading aberrant transcripts with premature termination codons, and aberrant NMD has been linked to neurodevelopmental disorders (NDD). A key player of NMD is UPF1, which is a helicase. Including the current patient, only four individuals with NDD and UPF1 variants have been reported in the ...
Zeynep Tümer +4 more
wiley +1 more source
Prp43: An RNA helicase-like factor involved in spliceosome disassembly [PDF]
, 1997 Jaime E. Arenas, John Abelson
openalex +1 more source
Virus-encoded RNA helicases [PDF]
Journal of Virology, 1997 G Kadaré, A L Haenni
openaire +3 more sources
Cell Proliferation, EarlyView.To identify genetic events that can lead to tumour death once either MLH1 or TP53 is mutated, a genome‐wide genetic screening was performed, uncovering a list of putative hits. Synthetic lethal interactions were validated either genetically or chemically by using small molecules that inhibit these genes either in vitro and in vivo.
Rivki Cashman +12 more
wiley +1 more source
Cell Proliferation, EarlyView.A potent combination of small molecules YFSS (Y27632, Forskolin, SB431542, SP600125) that were screened through a neuronal‐specific promoter–reporter system TUBB3::mCherry effectively induces neuronal‐GBM conversion in vitro and in vivo, unveiling molecular mechanisms that offer a theoretical basis and a potential therapeutic strategy for treating GBM.
Ya'nan Hu +12 more
wiley +1 more source