Results 41 to 50 of about 125,618 (325)

Snf2 family ATPases and DExx box helicases:differences and unifying concepts from high-resolution crystal structures [PDF]

, 2006
Proteins with sequence similarity to the yeast Snf2 protein form a large family of ATPases that act to alter the structure of a diverse range of DNA–protein structures including chromatin. Snf2 family enzymes are related in sequence to DExx box helicases,
Aasland, Ahne, Akhtar, Andrew Flaus, Asturias, Auble, Auble, Auble, Bazett-Jones, Becker, Beerens, Bouazoune, Boyer, Boyer, Briggs, Caruthers, Corona, Cote, Dasgupta, Davis, Deaconescu, Dhalluin, Dumont, Durr, Eisen, Fan, Fitzgerald, Flaus, Flaus, Goldmark, Gorbalenya, Grune, Harald Dürr, Havas, Hishida, Ito, Jaskelioff, Kagalwala, Karl-Peter Hopfner, Kawaoka, Kim, Laurent, Laurent, Levin, Levin, Lia, Mahdi, Mannhaupt, Mizuguchi, Morillon, Myong, Peterson, Petukhova, Petukhova, Phelan, Pray-Grant, Quinn, Richmond, Ristic, Saha, Saha, Schild, Sengoku, Serebrov, Shen, Shinohara, Simic, Sims, Singleton, Singleton, Singleton, Smith, Soultanas, Sprouse, Stanley, Studitsky, Subramanya, Sukhodolets, Svejstrup, Swagemakers, Tai, Thoma, Tom Owen-Hughes, Tran, Tsukiyama, van den Boom, van Gool, Van Komen, Velankar, Wang, Whitehouse, Woudstra, Yu, Yu, Zhang, Zofall   +95 more
core   +3 more sources

DHX36 enhances RIG-I signaling by facilitating PKR-mediated antiviral stress granule formation. [PDF]

PLoS Pathogens, 2014
RIG-I is a DExD/H-box RNA helicase and functions as a critical cytoplasmic sensor for RNA viruses to initiate antiviral interferon (IFN) responses. Here we demonstrate that another DExD/H-box RNA helicase DHX36 is a key molecule for RIG-I signaling by ...
Ji-Seung Yoo, Kiyohiro Takahasi, Chen Seng Ng, Ryota Ouda, Koji Onomoto, Mitsutoshi Yoneyama, Janice Ching Lai, Simon Lattmann, Yoshikuni Nagamine, Tadashi Matsui, Kuniyoshi Iwabuchi, Hiroki Kato, Takashi Fujita   +12 more
doaj   +1 more source

Localisation of the human hSuv3p helicase in the mitochondrial matrix and its preferential unwinding of dsDNA [PDF]

, 2002
We characterised the human hSuv3p protein belonging to the family of NTPases/helicases. In yeast mitochondria the hSUV3 orthologue is a component of the degradosome complex and participates in mtRNA turnover and processing, while in Caenorhabditis ...
Awiszus, K., Bartnik, E., Borowski, P., Dmochowska, A., Dziembowski, A., Minczuk, M., Papworth, M.A., Piwowarski, J., Schalinski, S., Stepien, P.P., Tokatlidis, K.   +10 more
core   +2 more sources

Roles of the linker region of RNA helicase A in HIV-1 RNA metabolism. [PDF]

PLoS ONE, 2013
RNA helicase A (RHA) promotes multiple steps in HIV-1 production including transcription and translation of viral RNA, annealing of primer tRNA(Lys3) to viral RNA, and elevating the ratio of unspliced to spliced viral RNA.
Li Xing, Meijuan Niu, Xia Zhao, Lawrence Kleiman   +3 more
doaj   +1 more source

The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription. [PDF]

PLoS ONE, 2016
RNA helicase family members exhibit diverse cellular functions, including in transcription, pre-mRNA processing, RNA decay, ribosome biogenesis, RNA export and translation.
Nian Xiang, Miao He, Musarat Ishaq, Yu Gao, Feifei Song, Liang Guo, Li Ma, Guihong Sun, Dan Liu, Deyin Guo, Yu Chen   +10 more
doaj   +1 more source

A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance

mBio, 2023
Coronaviruses (CoVs) encode nonstructural proteins 1–16 (nsps 1–16) which form replicase complexes that mediate viral RNA synthesis. Remdesivir (RDV) is an adenosine nucleoside analog antiviral that inhibits CoV RNA synthesis.
Samantha L. Grimes, Young J. Choi, Anoosha Banerjee, Gabriel Small, Jordan Anderson-Daniels, Jennifer Gribble, Andrea J. Pruijssers, Maria L. Agostini, Alexandra Abu-Shmais, Xiaotao Lu, Seth A. Darst, Elizabeth Campbell, Mark R. Denison   +12 more
doaj   +1 more source

Human Enterovirus Nonstructural Protein 2CATPase Functions as Both an RNA Helicase and ATP-Independent RNA Chaperone.

PLoS Pathogens, 2015
RNA helicases and chaperones are the two major classes of RNA remodeling proteins, which function to remodel RNA structures and/or RNA-protein interactions, and are required for all aspects of RNA metabolism.
Hongjie Xia, Peipei Wang, Guang-Chuan Wang, Jie Yang, Xianlin Sun, Wenzhe Wu, Yang Qiu, Ting Shu, Xiaolu Zhao, Lei Yin, Cheng-Feng Qin, Yuanyang Hu, Xi Zhou   +12 more
doaj   +1 more source

RNA helicase 3.6.4.13 [PDF]

, 2013
EC number  3.6.4.13 Systematic name  ATP phosphohydrolase (RNA helix unwinding) Recommended name  RNA helicase Synonyms  1a NTPase/helicase [5]  ATP/dATP-dependent RNA helicase [32]  ATPase [1,36]  ATPase/RNA helicase [32]  ATPase/helicase [36,41]  BMV 1a protein [5]  BmL3-helicase [32]  Brr2p [50]  DBP2 [30]  DDX17 [12]  DDX19 [56]  DDX25 [
Schomburg, Dietmar, Schomburg, Ida
openaire   +1 more source

Viral sensing by RNA helicases

Virologie, 2020
A key aspect of antiviral immunity is the distinction between "self" and "non-self" components. This distinction can be established through the detection of double-stranded RNA (dsRNA), a common sign of viral infection, by cytosolic RNA helicases.
Rousseau, Claire, Meignin, Carine
openaire   +6 more sources

RNA turnover: The helicase story unwinds [PDF]

Current Biology, 1996
AbstractRecent results show that RNA helicases play important roles in RNA decay, both as exoribonuclease accessory factors and in communicating signals to RNA decay machinery.
John S. Jacobs Anderson, Roy Parker
openaire   +3 more sources