Results 161 to 170 of about 1,270,992 (292)
Single-molecule experiments in biological physics: methods and
applications
, 2006 I review single-molecule experiments (SME) in biological physics. Recent
technological developments have provided the tools to design and build
scientific instruments of high enough sensitivity and precision to manipulate
and visualize individual ..., , , , , Adachi K, Adelman K, Ahsan A, Alberts B, Allahverdyan A, Allemand J F, Altan-Bonnet G, Ashkin A, Ashkin A, Ashkin A, Ashkin A, Ashkin A, Ashkin A, Astumian R D, Astumian R D, Baumann C G, Baumann C G, Bell G I, Bennett C H, Bennink M L, Bennink M L, Bensimon D, Best R B, Bhasin N, Bhattacharjee S M, Bhattacharjee S M, Binnig G, Binnig G, Blanchard S C, Blickle V, Block S M, Block S M, Bloomfield V A, Bochkov G N, Bockelmann U, Boroudjerdi H, Bouchiat C, Braslavsky I, Brower-Toland B D, Brujic J, Bryant Z, Bundschuh R, Burgess S A, Bustamante C, Bustamante C, Bustamante C, Bustamante C, Calladine C R, Carl P, Carrion-Vazquez M, Carrion-Vazquez M, Carrion-Vazquez M, Carter N J, Carter N J, Causo M S, Charvin G, Chatenay D, Chen S-J, Ciliberto S, Clausen-Schaumann H, Cluzel P, Cocco S, Cocco S, Cocco S, Cocco S, Cocco S, Cohen E G D, Cohen E G D, Cohen E G D, Crooks G E, Crooks G E, Cross R A, Cuesta-Lopez S, Cui Y, Cui Y, Cule D, Czajkowsky D M, Córdova N J, Daban J R, Dammer U, Dammer U, Danilowicz C, Davenport R J, De Duve C, Dekker N H, Deng H, Discher D E, Dohoney K M, Douarche F, Eisenberg E, Engel A, Essevaz-Roulet B, Evans D J, Evans E, Evans E, Evans E, Evans E, Evans E, F Ritort, Fain B, Fernandez J M, Fernandez J M, Fernandez J M, Finer J T, Finkelstein A V, Finzi L, Fisher M E, Florin E L, Flyvbjerg H, Forde N R, Forkey J N, Frank-Kamentskii M D, Frechet J M, Fritz J, Fréchet J M J, Gallavotti G, Garces-Chavez V, Garcia-Manyes S, Gelles J, Gelles J, Gelles J, Gergely C, Gerland U, Gerland U, Gerland U, Gestland R F, Goel A, Goel A, Gordon M P, Gore J, Gore J, Gosse C, Grange W, Green N H, Grier D G, Gross D H E, Ha T, Ha T, Hafner J H, Hanggi P, Hanke A, Hanley W, Hansen J C, Haran G, Harlepp S, Herschlag D, Higgs P G, Hill T L, Hill T L, Hinterdorfer P, Howard J, Hummer G, Hummer G, Hwa T, Hyeon C, Inoue A, Isralewitz B, Jarzynski C, Jarzynski C, Jarzynski C, Jarzynski C, Jensen M O, Jeruzalmi D, Junier I Ritort F, Jülicher F, Kafri Y, Katritch V, Kawakami M, Keller D, Keller D, Kellermayer M S K, Kellermayer M S, Kim H D, Kindt J, Kitamura K, Klimov D K, Klug A, Konrad M W, Kosikov K M, Kosztin I, Kramers H A, Kukowska-Latallo J F, Kunze K-K, Kurchan J, Kühner F, Ladoux B, Lang M J, Lang M J, Law R, Lebowitz J L, Lebrun A, Lee G U, Lee G U, Leger J F, Leuba S H, Leuva S H, Lhua R C, Li P T X Bustamante C Tinoco I, Liphardt J, Liu F, Lu H, Léger J F, Maes C, Maes C, Maier B, Manosas M, Manosas M Wen J D Li P T X Smith S B Bustamante C Tinoco I Ritort F, Marko J, Marko J, Marko J F, Marszalek P E, Marszalek P E, Marszalek P E, Masaike T, Mathews D H, Mazonka O Jarzynski C, McGurn A R, Merkel R, Min W, Moffitt J R, Molloy J E, Moy V T, Muller D J, Munoz V, Müller D J, Müller M, Müller M, Nayashima M, Nelson D R, Nguyen T T Grossberg A Y Shklovskii B I Holm C Kekicheff P Podgornik R, Noji H, Noy A, Oberhauser A F, Onoa B, Onoa B, Onuchic J N, Oono Y, Orland H, Orlandini E, Orphanides G, Paci E, Pagnani A, Pan J, Pant K, Park S, Pauling L, Perret E, Peyrard M, Phillips W D, Poirier M G, Poland D, Poland D, Purohit P K, Qian H, Qu X, Rief M, Rief M, Rief M, Rief M, Rief M, Rief M, Ritort F, Ritort F, Ritort F, Ritort F, Ros R, Rouzina I, Rouzina I, Rubinstein M, Saleh O A, Sarkar A, Schiessel H, Schiessel H, Schlierf M, Schroeder R, Schumakovitch I, Schurr J M, Schwesinger F, Seifert U, Sellers J R, Shaevitz J W, Smith B L, Smith D E, Smith S B, Soong R K, Sosnick T R, Speck T, Spudich A, Strick T, Strick T R, Strick T R, Strick T R, Strunz T, Svoboda K, Tanaka H, Thirumalai D, Thurmond K B, Tinoco I, Tinoco I, Tinoco I, Tinoco I, Tinoco I, Treiber D K, Treiber D K, Trepagnier E H, Tsallis C, Uemura S, Uptain S M, Valpuesta J M, Vanzi F, Veigel C, Veigel C, Visscher K, Vologodskii A, Wang M D, Wang M D, Wartell R M, Watson J D, Watson J D, Wen J D Manosas M Li P T X Smith S B Bustamante C Ritort F Tinoco I, Wenner J R, Widom J, Wiita A P, Wilkins M H F, Williams M C, Williams M C, Williams M C, Williams P M, Williams P M, Wood R H, Woodcock C L, Wuite G J L, Xie Z, Yager T D, Yang G, Yasuda R, Yasuda R, Yildiz A, Yildiz A, Yin H, Zandi R, Zarrinkar P, Zhou H, Zhuang X, Zuckermann D M, Zuker M, Zwanzig R W +351 morecore +1 more sourceRNA helicases [PDF]
RNA Biology, 2013 Similar to proteins, RNA molecules must fold into the correct conformation and associate with protein complexes in order to be functional within a cell. RNA helicases rearrange RNA secondary structure and RNA-protein interactions in an ATP-dependent reaction, performing crucial functions in all aspects of RNA metabolism.openaire +2 more sourcesOncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT
Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher +2 morewiley +1 more sourceVelocity and processivity of helicase unwinding of double-stranded
nucleic acids
, 2005 Helicases are molecular motors which unwind double-stranded nucleic acids
(dsNA) in cells. Many helicases move with directional bias on single-stranded
(ss) nucleic acids, and couple their directional translocation to strand
separation.Bhattacharjee S M, Doering C, F Jülicher, Klein G A, Korolev S, Lohman T M, M D Betterton, Perkins T T, Peskin C S, Stukalin E B +9 morecore +1 more sourceLPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT
Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang +4 morewiley +1 more sourceDeciphering the soybean root rot pathogen Phytophthora sojae: Signaling pathways, transcriptional regulation, and effector biology
New Plant Protection, EarlyView.This review highlights how Phytophthora sojae utilizes unconventional lineage‐specific signaling networks, including unique G protein‐coupled receptor fusions, expanded kinases, and rapidly evolving effectors, to infect soybeans. Understanding these divergent molecular paradigms reveals critical vulnerabilities in this destructive pathogen, offering ...Min Qiu, Xiaoyi Zhang, Bo Yang, Wenwu Ye, Yuanchao Wang +4 morewiley +1 more sourceSplit-APEX implicates splicing factor SRSF1 and splicing helicases in ribosomal biogenesis
Frontiers in Molecular BiosciencesSR proteins are RNA-binding proteins with one or two RNA recognition motif (RRM)-type RNA-binding domains and a C-terminal region rich in arginine-serine dipeptides. They function in cellular processes ranging from transcription to translation.Vasileios Paschalis, Vasileios Paschalis, Max F. K. Wills, Max F. K. Wills, Philippe De Gusmao Araujo, Philippe De Gusmao Araujo, Christian Lucas, Christian Lucas, Sumera Tubasum, Sumera Tubasum, Shijie Cui, Shijie Cui, Hesna Kara, Hesna Kara, Carlos Bueno-Alejo, Carlos Bueno-Alejo, Marina Santana-Vega, Andrea Taladriz-Sender, Zhengyun Zhao, Alexander Axer, Cyril Dominguez, Cyril Dominguez, Alasdair W. Clark, Glenn A. Burley, Andrew J. Hudson, Andrew J. Hudson, Ian C. Eperon, Ian C. Eperon +27 moredoaj +1 more sourceGenetic analysis of primary lung interdigitating dendritic cell sarcomas
The Journal of Pathology, EarlyView.Abstract
Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper +6 morewiley +1 more source
