RNA helicases DDX3X and DDX3Y form nanometer-scale RNA-protein clusters that support catalytic activity. [PDF]
Yanas A +4 more
europepmc +1 more source
Extranodal natural killer/T‐cell lymphoma: From fatal to curable
Abstract Extranodal natural killer (NK)/T‐cell lymphoma (ENKTCL) is one of the most aggressive non‐Hodgkin lymphomas characterized by NK‐cell or T‐cell origins, a geographic prevalence in Asian and South American populations, and Epstein–Barr virus (EBV) infection.
Jie Xiong +12 more
wiley +1 more source
The nuclear GUCT domain-containing DEAD-box RNA helicases govern gametophytic and sporophytic development in Physcomitrium patens. [PDF]
Perroud PF +8 more
europepmc +1 more source
A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases
Protein kinases (PKs) are enzymes that catalyze phosphorylation of protein substrates involved in a wide variety of biological signalling pathways. This review describes the different families and mechanisms of action and regulation of protein kinases, together with the different classes of fluorescent biosensors that have been engineered and ...
Timothe Abbura, May C. Morris
wiley +1 more source
Post-transcriptional cross- and auto-regulation buffer expression of the human RNA helicases <i>DDX3X</i> and <i>DDX3Y</i>. [PDF]
Rengarajan S +4 more
europepmc +1 more source
A synthetic methodology for the preparation of asymmetric benzene‐1,4‐disulfonamides was developed and applied to generate potential anti‐dengue virus (DENV) compounds. Guided by computer‐assisted structural rationalization, we designed synthetically more accessible analogs with reduced toxicity that interact with the DENV NS5 domain, thereby ...
Jakub Janáč +8 more
wiley +1 more source
Mitochondrial RNA Helicases: Key Players in the Regulation of Plant Organellar RNA Splicing and Gene Expression. [PDF]
Mizrahi R, Ostersetzer-Biran O.
europepmc +1 more source
What's new? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte +10 more
wiley +1 more source
Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes. [PDF]
Fujita KI +11 more
europepmc +1 more source

