Results 241 to 250 of about 1,508,120 (294)

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

open access: yesAdvanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao   +27 more
wiley   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

open access: yesAdvanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin   +20 more
wiley   +1 more source

RNA interference and turnover in plants -a complex partnership. [PDF]

open access: yesFront Plant Sci
Krzyszton M   +2 more
europepmc   +1 more source

Approach to Design of Potent RNA Interference-Based Preparations Against Hepatocellular Carcinoma-Related Genes. [PDF]

open access: yesInt J Mol Sci
Chernov PV   +11 more
europepmc   +1 more source

Enhanced Soybean Immunity to the Soybean Mosaic Virus Through RNA Interference Targeting the <i>CP</i> Gene. [PDF]

open access: yesPlants (Basel)
Wang T   +10 more
europepmc   +1 more source

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