CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao +27 more
wiley +1 more source
Patient-centered and coordinated therapy with RNA interference-based givosiran for acute hepatic porphyria: real-life experience for an ultra-rare disease from Romania. [PDF]
Bancos A +10 more
europepmc +1 more source
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin +20 more
wiley +1 more source
RNA Interference Targeting <i>MaCht-2</i> Induces Severe Molting Defects and Lethality in <i>Monochamus alternatus</i>. [PDF]
Fang S, Chang X, Chen H, Shi J.
europepmc +1 more source
RNA interference targeting lipoprotein(a): A "big hit" against "little a"? [PDF]
Stewart DJ, Rayner KJ.
europepmc +1 more source
RNA interference and turnover in plants -a complex partnership. [PDF]
Krzyszton M +2 more
europepmc +1 more source
Approach to Design of Potent RNA Interference-Based Preparations Against Hepatocellular Carcinoma-Related Genes. [PDF]
Chernov PV +11 more
europepmc +1 more source
Enhanced Soybean Immunity to the Soybean Mosaic Virus Through RNA Interference Targeting the <i>CP</i> Gene. [PDF]
Wang T +10 more
europepmc +1 more source

