Results 271 to 280 of about 389,091 (306)
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1982
Publisher Summary RNA methylation gives rise to a variety of methylated nucleotides and methylated derivatives of all the base components of RNA are known. RNA methyltransferases catalyze the post-transcriptional modification of RNA, and methylated nucleosides are present in rRNA and mRNA as well as in tRNA.
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Publisher Summary RNA methylation gives rise to a variety of methylated nucleotides and methylated derivatives of all the base components of RNA are known. RNA methyltransferases catalyze the post-transcriptional modification of RNA, and methylated nucleosides are present in rRNA and mRNA as well as in tRNA.
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RNA-directed DNA methylation in plants
Plant Cell Reports, 2015In plants, many small interfering RNAs (siRNAs) direct de novo methylation by DNA methyltransferase. DNA methylation typically occurs by RNA-directed DNA methylation (RdDM), which directs transcriptional gene silencing of transposons and endogenous transgenes. RdDM is driven by non-coding RNAs (ncRNAs) produced by DNA-dependent RNA polymerases IV and V
Ali, Movahedi +7 more
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Targets of RNA-directed DNA methylation
Current Opinion in Plant Biology, 2007RNA-directed DNA methylation contributes substantially to epigenetic regulation of the plant genome. Methylation is guided to homologous DNA target sequences by 24 nt 'heterochromatic' small RNAs produced by nucleolar-localized components of the RNAi machinery and a plant-specific RNA polymerase, Pol IV.
Marjori, Matzke +4 more
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Methylation of Mouse Ribosomal RNA Genes
DNA, 1982Ribosomal DNA (rDNA) methylation was studied in various strains of mice. We used restriction enzymes that are sensitive to methylation and a cloned probe containing the transcribed spacer and part of the 18S and 28S gene. Strains C3H/He3, C57/B6-3, and AKR/J were found to have less than 9% of the rDNA methylated.
J G, Reilly, C A, Thomas, M J, Lundell
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Pausing pluripotency via RNA methylation
Nature Cell Biology, 2023Xueting Xu, Baoming Qin
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Trends in Biochemical Sciences, 1976
Abstract Eukaryotic messenger RNA molecules contain methylated nucleotides, both at their 5′-terminal end in a unique ‘cap' structure, and internally as 6-methyladenylic acid. Similar methylation patterns are.found in heterogeneous nuclear RNA molecules.
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Abstract Eukaryotic messenger RNA molecules contain methylated nucleotides, both at their 5′-terminal end in a unique ‘cap' structure, and internally as 6-methyladenylic acid. Similar methylation patterns are.found in heterogeneous nuclear RNA molecules.
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LC-MS Analysis of Methylated RNA
2017The detection and quantification of methylated RNA can be beneficial to understand certain cellular regulation processes such as transcriptional modulation of gene expression, immune response, or epigenetic alterations. Therefore, it is necessary to have methods available, which are extremely sensitive and accurate, for instance liquid chromatography ...
Kathrin, Thüring +3 more
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The methylation of transfer RNA by methyl cobamide
Biochemical and Biophysical Research Communications, 1966W S, Walerych +2 more
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Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
exaly