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Small Nucleolar RNAs Guide Ribosomal RNA Methylation
Science, 1996Two recent reports, one in Cell and one in the Journal of Molecular Biology , show that the newly described small nucleolar RNAs control the site of methylation of the ribosomal RNA (rRNA). Tollervey explains how these small RNAs accomplish this targeting and discusses the possible role of ...
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RNA m6A methylation at the juxtaposition of apoptosis and RNA therapeutics
Trends in Cell BiologyTargeting RNA m6A marks in apoptosis-related transcripts holds promise for RNA therapeutics. However, pathway-specific RNA m6A sites on pro- or antiapoptotic transcripts have not been fully unveiled, let alone characterized. This article summarizes the current knowledge and gaps in the cellular response modulated by apoptotic stimulus-specific RNA m6A ...
Bünyamin Akgül +2 more
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The methylation of transfer RNA by methyl cobamide
Biochemical and Biophysical Research Communications, 1966W S, Walerych +2 more
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1982
Publisher Summary RNA methylation gives rise to a variety of methylated nucleotides and methylated derivatives of all the base components of RNA are known. RNA methyltransferases catalyze the post-transcriptional modification of RNA, and methylated nucleosides are present in rRNA and mRNA as well as in tRNA.
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Publisher Summary RNA methylation gives rise to a variety of methylated nucleotides and methylated derivatives of all the base components of RNA are known. RNA methyltransferases catalyze the post-transcriptional modification of RNA, and methylated nucleosides are present in rRNA and mRNA as well as in tRNA.
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METTLing with RNA methylation in leukaemia
Nature Reviews Drug Discovery, 2021openaire +2 more sources
Changes in m6A RNA methylation contribute to heart failure progression by modulating translation
European Journal of Heart Failure, 2020Markus T Bohnsack +2 more
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Pausing pluripotency via RNA methylation
Nature Cell Biology, 2023Xueting Xu, Baoming Qin
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The roles of DNA, RNA and histone methylation in ageing and cancer
Nature Reviews Molecular Cell Biology, 2019Mark A. Dawson +2 more
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Principles of RNA methylation and their implications for biology and medicine
Biomedicine and Pharmacotherapy, 2020Qin Xiao, Xiao Zhu, Wenguo Fan
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