Results 201 to 210 of about 835,495 (286)

RNA modifications in cancer

Han Wu, Shi Chen, Xiang Li, Yuyang Li, He Shi, Yang Qing, Bin Shi, Yifei Tang, Zhuoheng Yan, Hao Yang, Dongxu Wang, Weiwei Liu   +11 more
openalex   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

Lactylation-Boosted m⁵C RNA Modification Drives Choroidal Neovascularization. [PDF]

Research (Wash D C)
Zuo S, Li L, Tang J, Ye F, Sok, Liu Y, Ge S, Jia R, Fan X, Chai P, Lu L.   +10 more
europepmc   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Frameshifting as a tool in analysis of transfer RNA modification and translation

, 2004
Ramunė Leipuvienė
openalex   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

ModiDeC: a multi-RNA modification classifier for direct nanopore sequencing. [PDF]

Nucleic Acids Res
Alagna N, Mündnich S, Miedema J, Pastore S, Lehmann L, Wierczeiko A, Friedrich J, Walz L, Jörg M, Butto T, Friedland K, Helm M, Gerber S.   +12 more
europepmc   +1 more source

Lactylation-Driven NSUN2-Mediated RNA m5C Modification Promotes Perineural Invasion in Pancreatic Cancer

Tianhao Huang, Chonghui Hu, Huimou Chen, Honghui Jiang, Tingting Li, Qing Tian, Rihua He, Yuan Yuan, Yong Jiang, Yu Zhou, Qing Lin, Xuebiao Wei, Rufu Chen, Shangyou Zheng   +13 more
openalex   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source