Results 221 to 230 of about 853,838 (334)

The latest progression of N6-methyladenosine (m⁶A) RNA modification in diabetes mellitus and diabetic complications. [PDF]

Front Endocrinol (Lausanne)
Yin G, Hong J, Shan G, Xu C, Li B, Yang D.   +5 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Transfer RNA Modification Enzymes from Thermophiles and Their Modified Nucleosides in tRNA [PDF]

, 2018
Hiroyuki Hori, Takuya Kawamura, Takako Awai, Anna Ochi, Ryota Yamagami, Chie Tomikawa, Akira Hirata   +6 more
openalex   +1 more source

RNA modification is the mark and strategy for host-microbe interactions. [PDF]

Cell Mol Life Sci
Tian Y, Wang X.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

The Neurofibromatosis Type I Messenger RNA Undergoes Base-Modification RNA Editing [PDF]

, 1996
G. R. Skuse, Amedeo Cappione, Mark P. Sowden, Linda J. Metheny, Harold C. Smith   +4 more
openalex   +1 more source

m5C RNA modification in colorectal cancer: mechanisms and therapeutic targets. [PDF]

J Transl Med
Wang J, Qi C, Wang R, Cao Y, Zhou Y, Ye G.   +5 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

m6A RNA modification in tumor-associated macrophages: emerging roles in cancer immunity. [PDF]

Front Immunol
Chen X, Pu S, Lian K, Li L, Jiang X.
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source