Results 21 to 30 of about 966,777 (273)
Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
, 2010 For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
core +3 more sources
Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis
Acta Pharmaceutica Sinica B, 2023 RNAs are involved in the crucial processes of disease progression and have emerged as powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of therapeutic RNA to the targeted location and precise detection of RNA markers ...
Mengnan Zhao +8 more
doaj +1 more source
Lipid nanomaterials-based RNA therapy and cancer treatment
Acta Pharmaceutica Sinica B, 2023 We summarize the most important advances in RNA delivery and nanomedicine. We describe lipid nanoparticle-based RNA therapeutics and the impacts on the development of novel drugs. The fundamental properties of the key RNA members are described.
Xingcai Zhang +4 more
doaj +1 more source
Molecules, 2020 Guanosine- and uridine-rich single-stranded RNA (GU-rich RNA) is an agonist of Toll-like receptor (TLR) 7 and TLR8 and induces strong immune responses. A nanostructured GU-rich RNA/DNA assembly prepared using DNA nanotechnology can be used as an adjuvant
Fusae Komura +4 more
doaj +1 more source
Systemic Delivery of Anti-miRNA for Suppression of Triple Negative Breast Cancer Utilizing RNA Nanotechnology [PDF]
ACS Nano, 2015 Peixuan Guo, William E Carson, Yi Shu
exaly +2 more sources
, 2022 Cancer nanotechnology is a growing, emerging area of cross-disciplinary research that aims to develop efficient, specific and noninvasive approaches to restore the health and well-being of all cancer patients through more effective diagnosis and ...
Chorilli, Marlus [UNESP] +2 more
core +1 more source
Unified Nanotechnology Format: One Way to Store Them All
Molecules, 2021 The domains of DNA and RNA nanotechnology are steadily gaining in popularity while proving their value with various successful results, including biosensing robots and drug delivery cages.
David Kuťák +4 more
doaj +1 more source
Advanced Science, 2020 Controlling the selective one‐to‐one conjugation of RNA with nanoparticles is vital for future applications of RNA nanotechnology. Here, the monofunctionalization of a gold nanoparticle (AuNP) with a single copy of RNA is developed for ultrasensitive ...
Taek Lee +7 more
doaj +1 more source
Lactoferrin-Conjugated Nanoparticles as New Antivirals
Pharmaceutics, 2022 Lactoferrin is an iron-binding glycoprotein with multiple functions in the body. Its activity against a broad spectrum of both DNA and RNA viruses as well as the ability to modulate immune responses have made it of interest in the pharmaceutical and food
Malgorzata Krzyzowska +6 more
doaj +1 more source
Versatile kit of robust nanoshapes self-assembling from RNA and DNA modules
Nature Communications, 2019 DNA and RNA have been used for nanotechnology applications, though rarely in combination. Here the authors report the use of RNA motifs as structural joints with DNA building blocks for enhanced construction of small multi-component nanoshapes.
Alba Monferrer +3 more
doaj +1 more source