Results 61 to 70 of about 966,777 (273)

Out-of-Plane Aptamer Functionalization of RNA Three-Helix Tiles

Nanomaterials, 2019
Co-transcriptionally folding RNA nanostructures have great potential as biomolecular scaffolds, which can be used to organize small molecules or proteins into spatially ordered assemblies.
Aradhana Chopra, Sandra Sagredo, Guido Grossi, Ebbe S. Andersen, Friedrich C. Simmel   +4 more
doaj   +1 more source

Novel Perspectives towards RNA-Based Nano-Theranostic Approaches for Cancer Management

Nanomaterials, 2021
In the fight against cancer, early diagnosis is critical for effective treatment. Traditional cancer diagnostic technologies, on the other hand, have limitations that make early detection difficult. Therefore, multi-functionalized nanoparticles (NPs) and
Rabia Arshad, Iqra Fatima, Saman Sargazi, Abbas Rahdar, Milad Karamzadeh-Jahromi, Sadanand Pandey, Ana M. Díez-Pascual, Muhammad Bilal   +7 more
doaj   +1 more source

An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing [PDF]

, 2013
Characterisation of RNA and its intermolecular interactions is increasing in importance as the inventory of known RNA functions continues to expand. RNA-RNA interactions are central to post-transcriptional gene regulation mechanisms in bacteria, and the ...
Darren M. Gowers (485354), Jack O Phillips, Anastasia J Callaghan, Vincent, H., Andrew R. Pickford (485355), Adam J Roberts, Louise E. Butt (485353), Stone, Carlanne, Charlotte E. Mardle (485352), Henderson, Charlotte, Adam J. Roberts (485350), Pickford, Andy, Carlanne M Stone, Roberts, Adam J., Butt, Louise, Charlotte A Henderson, Louise E Butt, Anastasia J. Callaghan (485356), Helen A Vincent, Charlotte E Mardle, Callaghan, Anastasia, Carlanne M. Stone (485351), Phillips, Jack, Jack O. Phillips (485348), Charlotte A. Henderson (485349), Gowers, Darren, Mardle, C., Andrew R Pickford, Helen A. Vincent (485347), Darren M Gowers, Henderson Charlotte A., Mardle Charlotte E., Callaghan Anastasia J., Pickford Andrew R., Phillips Jack O., Butt Louise E., Gowers Darren M., Vincent Helen A., Roberts Adam J., Stone Carlanne M.   +39 more
core   +2 more sources

Measuring the Economic Impact of Quantum-Dot Nanotechnology on Display/TV Industries

, 2022
Governments are asking policymakers to quantify the economic and social impact of those advanced technologies they support, including nanotechnology. National policymakers and researchers who participated in OECD activities cooperated to develop a model ...
임정선
core   +1 more source

The Role of Viscoelasticity in Heterogeneous Glioblastoma Stem Cell Invasion in Biomimetic 3‐Dimensional Hydrogels

Advanced Healthcare Materials, EarlyView.
The role of viscoelasticity in the invasion of heterogeneous glioblastoma stem cells (GSCs) was investigated with GSCs categorized into subgroups based on molecular profile, as Reactive, Invasive, or Constructive using viscoelastic biomimetic hyaluronan‐oxime hydrogels.
Nicole J. Blaine, Arianna Skirzynska, Allysia A. Chin, Julie Audet, Molly S. Shoichet   +4 more
wiley   +1 more source

Artificial RNA Motifs Expand the Programmable Assembly between RNA Modules of a Bimolecular Ribozyme Leading to Application to RNA Nanostructure Design

Biology, 2017
A bimolecular ribozyme consisting of a core ribozyme (ΔP5 RNA) and an activator module (P5abc RNA) has been used as a platform to design assembled RNA nanostructures.
Md. Motiar Rahman, Shigeyoshi Matsumura, Yoshiya Ikawa   +2 more
doaj   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

Optimization of the Split-Spinach Aptamer for Monitoring Nanoparticle Assembly Involving Multiple Contiguous RNAs

Nanomaterials, 2019
The fact that structural RNA motifs can direct RNAs to fold and self-assemble into predictable pre-defined structures is an attractive quality and driving force for RNA’s use in nanotechnology.
Jack M. O’Hara, Dylan Marashi, Sean Morton, Luc Jaeger, Wade W. Grabow   +4 more
doaj   +1 more source

A novel nano‐immunotherapeutic remodels the immune landscape of malignant pleural effusion: Insights into its mechanism of action through single‐cell RNA‐sequencing

Clinical and Translational Medicine, 2022
Clinical evidence indicates that the microenvironment in malignant pleural effusion (MPE) is immunologically cold, which impairs tumour immunosurveillance and antitumor immune response to immune checkpoint blockade (ICB).
Yang Liu, Dawen Zhao
doaj   +1 more source

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source