Results 81 to 90 of about 966,777 (273)

Nanotechnology and business opportunities: scenarios as awareness instrument [PDF]

For a few years now, nanotechnology has been recognised as a promising new growth innovator. This leads to a shift from the exploration of nanotechnology knowledge towards a phase of exploitation. The coming years this commercialisation of nanotechnology
WHC Knol
core  

Strategic plan for NIOSH nanotechnology research and guidance : filling the knowledge gaps [PDF]

"Nanotechnology - the manipulation of matter on a near-atomic scale to produce new materials - has the potential to transform many industries, from medicine to manufacturing, and the products they produce.

core   +1 more source

The challenges of "upstream" communication and public engagement for Irish nanotechnology [PDF]

, 2009
This paper sets out some challenges for Ireland’s contribution to nanotechnology public engagement in the context of current STS and science communication theoretical practice approaches.
Murphy, Padraig
core   +2 more sources

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

Advanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann   +16 more
wiley   +1 more source

Effects of Double-Stranded RNA Degrading Nucleases on RNAi Efficiency in Beet Moth Spodoptera exigua (Lepidoptera: Noctuidae)

Insects
The insect order Lepidoptera contains many species that are considered to be agricultural pests. Specific double-stranded RNA-degrading enzymes in some moth species decrease the efficiency of RNA interference (RNAi).
Guandi Wang, Qian Wang, Wenrui Liu, Jingxin Wen, Yubo Yang, Zhilong Niu, Wei Guo, Dan Zhao   +7 more
doaj   +1 more source

A Critical Call for Mechanistic Investigations of Metal‐Bacteria Interactions

Advanced Materials, EarlyView.
It is well established that the antibacterial properties of metals have tremendous importance for bioengineering applications. What is not as appreciated, however, is the reproducibility crisis in this field's vast literature. In this perspective, we highlight this reproducibility problem, discuss its sources, and suggest solutions towards focused ...
J. Rackwitz, A. Bandyopadhyay, S. Belkin, S. Bose, N. Eliaz, J. L. Gilbert, T. C. Lowe, F. Mücklich, R. J. Turner, C. C. Tasan   +9 more
wiley   +1 more source

Recent Advancements in Cancer RNA-interference Therapy with Nanotechnology Strategies

Journal of Cancer Biomoleculars and Therapeutics
Cancer is a global challenge, and genetics play a major role in onsets and in designing the next generation of cancer therapies. One of the key approaches is the downregulation of genes through RNA interference (RNAi) which has been proposed as a ...
Ahmed Kh. Abosalha, Paromita Islam, Jacqueline L. Boyajian, Amal Kassab, Stephanie Makhlouf, Madison Santos, Satya Prakash   +6 more
doaj   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

Single-molecule force spectroscopy of toehold-mediated strand displacement

Nature Communications
Toehold-mediated strand displacement (TMSD) is extensively utilized in dynamic DNA nanotechnology and for a wide range of DNA or RNA-based reaction circuits.
Andreas Walbrun, Tianhe Wang, Michael Matthies, Petr Šulc, Friedrich C. Simmel, Matthias Rief   +5 more
doaj   +1 more source