Results 11 to 20 of about 2,226,379 (341)

Architecture of the spinach plastid-encoded RNA polymerase [PDF]

Nature Communications
The plastid-encoded RNA polymerase serves as the principal transcription machinery within chloroplasts, transcribing over 80% of all primary plastid transcripts.
Tongtong Wang, Guang-Lei Wang, Ying Fang, Yi Zhang, Wenxin Peng, Yue Zhou, Aihong Zhang, Long-Jiang Yu, Congming Lu   +8 more
doaj   +2 more sources

Structural Biology of Bacterial RNA Polymerase

Biomolecules, 2015
Since its discovery and characterization in the early 1960s (Hurwitz, J. The discovery of RNA polymerase. J. Biol. Chem. 2005, 280, 42477–42485), an enormous amount of biochemical, biophysical and genetic data has been collected on bacterial RNA ...
Katsuhiko S. Murakami
doaj   +2 more sources

Suppression by RNA Polymerase I Inhibitors Varies Greatly Between Distinct RNA Polymerase I Transcribed Genes in Malaria Parasites [PDF]

Pathogens
The transcription of ribosomal RNA (rRNA) by RNA Polymerase I (Pol I) is the rate-limiting step in ribosome biogenesis and a major determinant of cellular growth rates.
Hermela Samuel, Riward Campelo Morillo, Björn F. C. Kafsack   +2 more
doaj   +2 more sources

Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase

Nature Communications, 2017
The Zika virus outbreak is a global health threat and there is an urgent need for drugs against the virus. Here the authors present the structure of the RNA-dependent RNA-polymerase domain from Zika non-structural protein 5, which is a template for the ...
Andre S. Godoy, Gustavo M. A. Lima, Ketllyn I. Z. Oliveira, Naiara U. Torres, Fernando V. Maluf, Rafael V. C. Guido, Glaucius Oliva   +6 more
doaj   +2 more sources

Evolution of complex RNA polymerases: the complete archaeal RNA polymerase structure.

PLoS Biology, 2009
The archaeal RNA polymerase (RNAP) shares structural similarities with eukaryotic RNAP II but requires a reduced subset of general transcription factors for promoter-dependent initiation.
Yakov Korkhin, Ulug M Unligil, Otis Littlefield, Pamlea J Nelson, David I Stuart, Paul B Sigler, Stephen D Bell, Nicola G A Abrescia   +7 more
doaj   +5 more sources

Abstract P-23: Histone N-terminal Tails Reduce Early Nucleosomal Pausing during Transcription [PDF]

International Journal of Biomedicine, 2021
Background: Nucleosomes are the barriers to transcript elongation by RNA polymerase 2 (Pol 2) in vitro and in vivo. Formation and overcoming the barrier are important for transcription regulation. N-terminal tails of core histones do not affect the inner
Nadezhda S. Gerasimova, Fu-Kai Hsieh, Vasily M. Studitsky   +2 more
doaj   +1 more source

Abstract P-18: Phosphorylation of RNA Polymerase II C-Terminal Domain Affects Transcript Elongation Through Chromatin [PDF]

International Journal of Biomedicine, 2021
Background: Transcription is the central point of gene regulation where the efficient maintenance of chromatin structure during the passage of RNA polymerase (Pol II) is critical for cell survival and functioning.
Sohail Akhtar, Elena Y. Kotova, Nadezhda S. Gerasimova, Vasily M. Studitsky   +3 more
doaj   +1 more source

Single molecules characterization of transcription of bacterial RNA-polymerase parameters using acoustic force spectroscopy

St. Petersburg Polytechnical University Journal: Physics and Mathematics, 2022
This work presents the results of single-molecular studies of the effect of magnesium ions on the dynamic characteristics of transcription elongation of bacterial RNA polymerase.
Arseniev Anatolii, Panfilov Mikhail, Pobegalov Georgii, Potyseva Alina, Pavlinova Polina, Yakunina Maria, Khodorkovskiy Mikhail   +6 more
doaj   +1 more source

RNA Polymerases of Maize: Nuclear RNA Polymerases [PDF]

Proceedings of the National Academy of Sciences, 1971
Two DNA-dependent RNA polymerases of nuclear origin have been purified from leaves of Zea mays . The two enzymes can be separated on DEAE-cellulose columns. Enzymes I and II are eluted with 0.08 and 0.20 M (NH 4 ) 2 SO 4 , respectively.
Kathleen P. Mullinix, Lawrence Bogorad, Gustave C. Strain   +2 more
openaire   +3 more sources

Menadione and hydrogen peroxide trigger specific alterations in RNA polymerases profiles in quiescent Saccharomyces cerevisiae cells

Biotechnology & Biotechnological Equipment, 2021
Yeasts Saccharomyces cerevisiae, like other microbes in nature, respond to the unavailability of nutrients with entrance in quiescent/G0 state. These cells exist in non-dividing, latent form by maintaining the cellular metabolism at a low level but still
Asya Vladimirova Daskalova, Anna Atanasova Tomova, Anna Vangelova Kujumdzieva, Lyudmila Georgieva Velkova, Pavlina Aleksandrova Dolashka, Ventsislava Yankova Petrova   +5 more
doaj   +1 more source