Results 191 to 200 of about 768,924 (317)

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

Advanced Theory and Simulations, EarlyView.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak, Shivananda Kandagalla, Ramesh Sistla   +2 more
wiley   +1 more source

A New Synthetic RNA-Dependent DNA Polymerase from Human Tissue Culture Cells [PDF]

, 1972
Bertold Fridlender, Michael Fry, Arthur H. Bolden, Arthur Weissbach   +3 more
openalex   +1 more source

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

Advanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang, Yousheng Wu, Xuanlin Su, Kaiwei Cai, Man Ke, Niu He, Huili Zhu, Zefeng Tan, Jielin Zhu, Wensheng He, Min Peng, Shiqing Zhang, Hongcheng Mai, Anding Xu, Dan Lu   +14 more
wiley   +1 more source

Corrigendum: RNA Polymerase III, Ageing and Longevity

Frontiers in Genetics, 2021
Yavuz Kulaberoglu, Yasir Malik, Gillian Borland, Colin Selman, Nazif Alic, Jennifer M. A. Tullet   +5 more
doaj   +1 more source

Structural insights into promoter-proximal pausing of RNA polymerase II at +1 nucleosome. [PDF]

Sci Adv
Naganuma M, Kujirai T, Ehara H, Uejima T, Ito T, Goto M, Aoki M, Henmi M, Miyamoto-Kohno S, Shirouzu M, Kurumizaka H, Sekine SI.   +11 more
europepmc   +1 more source

Inhalable Hsa‐miR‐30a‐3p Liposomes Attenuate Pulmonary Fibrosis

Advanced Science, EarlyView.
The study explores inhalable hsa‐miR‐30a‐3p‐loaded liposomes as a treatment for bleomycin‐induced pulmonary fibrosis in mice. Hsa‐miR‐30a‐3p is electroporated into liposomes and formulated into a dry powder for inhalation. Delivered via dry powder inhalation, it improves pulmonary function, promotes myofibroblast de‐differentiation by targeting CNPY2 ...
Shuo Liu, Kristen D. Popowski, Christina M. Eckhardt, Weihang Zhang, Junlang Li, Yujia Jing, Dylan Silkstone, Elizabeth Belcher, Megan Cislo, Shiqi Hu, Halle Lutz, Asma Ghodsi, Mengrui Liu, Phuong‐Uyen C. Dinh, Ke Cheng   +14 more
wiley   +1 more source

Cryo-EM structure of Nipah virus RNA polymerase complex. [PDF]

Sci Adv
Wang Y, Zhao L, Zhang Y, Wang Y, Tang J, Liu S, Gao H, Zhang X, Zinzula L, Kornberg RD, Zhang H.   +10 more
europepmc   +1 more source

RNA-Dependent DNA Polymerase Activity in Five RNA Viruses: Divalent Cation Requirements [PDF]

, 1970
E M Scolnick, Elaine Rands, Stuart A. Aaronson, George J. Todaro   +3 more
openalex   +1 more source

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

Advanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang, Zizhang Li, Jingyu Chen, Wenjing Yang, Xingxing He, Peng Wu, Feng Chen, Ziwei Zhou, Chenze Ren, Yuyan Shan, Xiewen Wen, Vassily A. Lyubetsky, Leonid Yu. Rusin, Xiaoshu Chen, Jian‐Rong Yang   +14 more
wiley   +1 more source

Amino acids and control of nucleolar size, the activity of RNA polymerase I, and DNA synthesis in liver.

, 1976
Raymond P. Bailey, Mary Jane Vrooman, Yasuko Sawai, Kinji Tsukada, Susan Short, I Lieberman   +5 more
openalex   +1 more source