Results 231 to 240 of about 1,275,536 (291)

Differential association of primary and alternative σ factors with RNA polymerase of Mycobacterium tuberculosis during transcription elongation. [PDF]

Nucleic Acids Res
Hazra N, Mukhopadhyay J.
europepmc   +1 more source

Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance

, 2019
Giulio Nannetti, Serena Massari, Beatrice Mercorelli, Chiara Bertagnin, Jenny Desantis, Giorgio Palù, Oriana Tabarrini, Arianna Loregian   +7 more
openalex   +2 more sources

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Paused RNA polymerase primes promoters via RNA-mediated stabilisation of transcription factor ERα. [PDF]

Nat Commun
Mann R, Soota D, Das A, Podh NK, Mehta G, Notani D.   +5 more
europepmc   +1 more source

Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III.

, 1993
Chao-Ming Chiang, Hui Ge, Zhiqiang Wang, Alexander Hoffmann, Robert G. Roeder   +4 more
openalex   +2 more sources

Harnessing Advances in Bone Tissue Engineering for Design of Bone‐on‐Chip Systems

Advanced Healthcare Materials, EarlyView.
Bone‐on‐chip (BoC) systems demonstrate significant potential as next‐generation models to study human (patho)physiology and evaluate new therapies. However, progress toward functional, human‐like BoCs has been hindered by the structural and functional complexity of bone. This perspective discusses how insights from bone tissue engineering can guide BoC
Farhad Sanaei, Yannick Hajee, Gerry L. Koons, David T. Wu, Sander C.G. Leeuwenburgh, Jeroen J.J.P. van den Beucken, Mani Diba   +6 more
wiley   +1 more source

Direct recruitment of RNA Polymerase II by NANOG to activated target genes

Mullin NP, Barbieri E, Zhang J, Vojtek M, McGarvey A, Colby D, Tomlinson S, Chambers IP.   +7 more
europepmc   +1 more source

Membranous Interacting Partners of Phage-Type Plastid RNA Polymerase Have Limited Impact on Plastid Gene Expression During Chloroplast Development. [PDF]

Plant Direct
Kurotaki Y, Hagiwara Y, Noto K, Nishino AS, Fujii S.   +4 more
europepmc   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

A Modular T7 RNA Polymerase Toolbox Linking Selective miRNA Detection to Signal Amplification and Protein Expression. [PDF]

J Am Chem Soc
Vonk-de Roy M, Walther A.
europepmc   +1 more source