Results 241 to 250 of about 2,226,379 (341)

Inhibitors of the hepatitis C virus RNA-dependent RNA polymerase

ARKIVOC, 2006
Barbara Attenni, Salvatore Avolio, Stefania Colarusso, Savina Malancona, Steven Harper, Sergio Altamura, Uwe Koch, Frank Narjes   +7 more
doaj   +1 more source

Current biosensing strategies based on in vitro T7 RNA polymerase reaction. [PDF]

Biotechnol Notes
Sumanto Marpaung DS, Yap Sinaga AO, Damayanti D, Taharuddin T, Gumaran S.   +4 more
europepmc   +1 more source

Bringing Attomolar Detection to the Point‐of‐Care with Nanopatterned DNA Origami Nanoantennas

Advanced Materials, EarlyView.
Single DNA molecules are captured within the hotspots of DNA origami NanoAntennas arranged on a chip surface. Fluorescence is amplified, enabling direct detection on a point‐of‐care‐compatible imaging setup (visualized as bright signals against a dark background).
Renukka Yaadav, Kateryna Trofymchuk, Mihir Dass, Vivien Behrendt, Benedikt Hauer, Jan Schütz, Cindy Close, Michael Scheckenbach, Giovanni Ferrari, Leoni Mäurer, Sophia Sebina, Viktorija Glembockyte, Tim Liedl, Philip Tinnefeld   +13 more
wiley   +1 more source

Distinct molecular structures of nuclear class I, II, and III DNA-dependent RNA polymerases.

, 1975
Virgil E. F. Sklar, Lawrence B. Schwartz, Robert G. Roeder   +2 more
openalex   +1 more source

Splicing of Nascent RNA Coincides with Intron Exit from RNA Polymerase II

Cell, 2016
Fernando Carrillo Oesterreich, Lydia Herzel, K. Straube, K. Hujer, J. Howard, K. Neugebauer   +5 more
semanticscholar   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

NDF/GLYR1 Promotes RNA Polymerase II Processivity via Pol II Binding and Nucleosome Destabilization. [PDF]

Int J Mol Sci
Li Z, Fei J.
europepmc   +1 more source

RNA polymerase II–associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II

Science, 2015
Ming Yu, Wenjing Yang, T. Ni, Zhanyun Tang, T. Nakadai, Jun Zhu, R. Roeder   +6 more
semanticscholar   +1 more source

In Situ Monitoring and Electrical Modulation of Cellular Behaviors Directly at the Cell–Electrode Interface

Advanced Materials Interfaces, EarlyView.
This study presents a platform for simultaneous monitoring and electrical control of cellular responses at the cell–electrode interface. The platform delivers tunable yet uniform electrical cues to cells, revealing that optimal electrical stimulation (ES) conditions vary across cell types.
Khandoker Asiqur Rahaman, Yeon Jae Chang, Hyeok Kim, Tae Kyoung Lee, Jaeyeon Jun, Min Jung Kim, Jimin Park, Hyung‐Seop Han   +7 more
wiley   +1 more source

RNA polymerase I is essential for driving the formation of 3D genome in early embryonic development in mouse, but not in human. [PDF]

Genome Med
Hou C, Tian GG, Hu S, Chen B, Li X, Xu B, Cao Y, Le W, Hu R, Chen H, Zhang Y, Fang Q, Zhang M, Wang Z, Zhang Z, Zhang J, Wei Z, Yao G, Wang Y, Yin P, Guo Y, Tong G, Teng X, Sun Y, Cao Y, Wu J.   +25 more
europepmc   +1 more source