Current biosensing strategies based on in vitro T7 RNA polymerase reaction. [PDF]
Sumanto Marpaung DS+4 more
europepmc +1 more source
Emerging Therapeutic Strategies for Hearing Loss
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han+9 more
wiley +1 more source
RNA-dependent DNA polymerase activity of RNA tumor viruses. V. Rous sarcoma virus single-stranded RNA-DNA covalent hybrids in infected chicken embryo fibroblast cells [PDF]
Jonathan Leis+3 more
openalex +1 more source
Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
B. Shu, P. Gong
semanticscholar +1 more source
Analysis of the In Vitro Product of an RNA-Dependent RNA Polymerase Isolated from Influenza Virus-Infected Cells [PDF]
Lawrence A. Caliguiri+1 more
openalex +1 more source
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak+2 more
wiley +1 more source
Structural insights into promoter-proximal pausing of RNA polymerase II at +1 nucleosome. [PDF]
Naganuma M+11 more
europepmc +1 more source
Localization of Escherichia coli RNA polymerase binding sites on bacteriophage S13 and 0X174 DNAs by electron microscopy [PDF]
Éric Rassart+2 more
openalex +1 more source
FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang+14 more
wiley +1 more source
T7 RNA polymerase-guided base editor for accelerated continuous evolution in <i>Bacillus subtilis</i>. [PDF]
Wang B+7 more
europepmc +1 more source