Results 351 to 360 of about 2,760,256 (386)
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Journal of Molecular Biology, 2000
Bacterial RNA polymerase and eukaryotic RNA polymerase II exhibit striking structural similarities, including similarities in overall structure, relative positions of subunits, relative positions of functional determinants, and structures and folding topologies of subunits.
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Bacterial RNA polymerase and eukaryotic RNA polymerase II exhibit striking structural similarities, including similarities in overall structure, relative positions of subunits, relative positions of functional determinants, and structures and folding topologies of subunits.
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Hepatitis C Virus RNA-Dependent RNA Polymerase (NS5B Polymerase)
2000Approximately 170 million people world-wide are chronically infected with the hepatitis C virus (HCV) (BRADLEY et al. 1983; CHOO et al. 1989; HOUGHTON 1996; A;LTER 1997; also see Thomas, this volume). Although chronic infection with HCV frequently produces no symptoms for 5–30 years, it eventually has adverse effects on the host and constitutes a major
C H, Hagedorn +2 more
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2004
At the end of the 1950s Hoagland and Zamecnik had succeeded in obtaining an in vitro protein synthesis from ribosomes and crude acellular extracts. Ribosomes cannot by themselves achieve a specific protein synthesis and require an information originating in last analysis in the genes.
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At the end of the 1950s Hoagland and Zamecnik had succeeded in obtaining an in vitro protein synthesis from ribosomes and crude acellular extracts. Ribosomes cannot by themselves achieve a specific protein synthesis and require an information originating in last analysis in the genes.
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RNA polymerase III transcription
Current Opinion in Cell Biology, 1991Remarkable progress has been made in defining the functional significance of the protein-DNA interactions involved in transcription complex formation on yeast tRNA and 5S RNA genes. This new information leads to a re-evaluation of how the class III gene transcription machinery operates.
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1973
Publisher Summary This chapter presents the status of RNA polymerases involved in RNA synthesis in mammalian cells, with emphasis on some recent developments in the field of nuclear RNA polymerase. The chapter discusses that the RNA polymerases of eukaryotic nuclei exist in multiple forms. These enzymes are compartmentalized within the nucleus.
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Publisher Summary This chapter presents the status of RNA polymerases involved in RNA synthesis in mammalian cells, with emphasis on some recent developments in the field of nuclear RNA polymerase. The chapter discusses that the RNA polymerases of eukaryotic nuclei exist in multiple forms. These enzymes are compartmentalized within the nucleus.
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Hepatitis C Virus RNA-Dependent RNA Polymerase (NS5B Polymerase)
2003The hepatitis C virus (HCV) chronically infects approx 4 million patients in the United States alone, and constitutes a major cause of chronic liver disease and hepatocellular carcinoma (1-3). Current antiviral therapies for chronic hepatitis C remain relatively ineffective and have significant side-effects in many patients.
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Use of T7 RNA polymerase to direct expression of cloned genes.
Methods in Enzymology, 1990F. Studier +3 more
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Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes.
Journal of Molecular Biology, 1986F. Studier, B. Moffatt
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Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction.
Science, 1992Peng Liang, A. Pardee
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