Results 221 to 230 of about 807,500 (308)

Stereochemistry of polymerization by DNA-dependent RNA-polymerase from Escherichia coli: An investigation with a diastereomeric ATP-analogue [PDF]

, 1977

openalex   +1 more source

Engineered MSC Aggregates with E/N‐Cadherin and IL‐6 Preconditioning for the Treatment of Systemic Sclerosis

Advanced Healthcare Materials, EarlyView.
Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang, Mengyuan Qian, Yirui Shi, Jiaxu Cao, Min Xu, Xin Wen, Yunxia Yan, Sha Liu, Hongwei Chen, Shanshan Liu, Jun Yang, Lingyun Sun   +11 more
wiley   +1 more source

CX-5461 induces radiosensitization through modification of the DNA damage response and not inhibition of RNA polymerase I. [PDF]

Sci Rep, 2022
Lehman SL, Schwartz KR, Maheshwari S, Camphausen K, Tofilon PJ.   +4 more
europepmc   +1 more source

Uranyl mediated photofootprinting reveals strongE.coliRNA polymerase-DNA backbone contacts in the +10 region of theDeoP1 promoter open complex [PDF]

, 1989
Claus Jeppesen, Peter E. Nielsen
openalex   +1 more source

Progress of Immune‐Inducible Biomaterials for Post‐Ablation Cancers

Advanced Healthcare Materials, EarlyView.
The presence of residual tumors after ablative therapies poses a significant challenge, generally resulting in recurrence and metastases. This review offers a concise overview of immune‐inducible biomaterials from the perspective of the cancer‐immunity cycle, and how they enhance antitumor immunity through diverse mechanisms following ablative ...
Shuangshuang Zhao, Zheng Zhang, Xincai Wu, Yanwei Chen, Wenjun Li, Jiayan Bao, Xin Zhang, Baoding Chen   +7 more
wiley   +1 more source

LINC01116-dependent upregulation of RNA polymerase I transcription drives oncogenic phenotypes in lung adenocarcinoma. [PDF]

J Transl Med
Sarkar SS, Sharma M, Saproo S, Naidu S.
europepmc   +1 more source

Transient-state kinetic analysis of multi-nucleotide addition catalyzed by RNA polymerase I. [PDF]

Biophys J, 2021
Ingram ZM, Schneider DA, Lucius AL.
europepmc   +1 more source

Biomimetic Scaffolds Enhance iPSC Astrocyte Progenitor Angiogenic, Immunomodulatory, and Neurotrophic Capacity in a Stiffness and Matrix‐Dependent Manner for Spinal Cord Repair Applications

Advanced Healthcare Materials, EarlyView.
Through tuning biomimetic scaffold stiffness and matrix composition the reparative capacity of astrocyte progenitors is enhanced. Soft, collagen‐IV/fibronectin‐functionalized scaffolds promote progenitor growth while improving angiogenic, immunomodulatory, and neurotrophic capacity in a stiffness and matrix‐dependent manner, demonstrating the impact of
Cian O'Connor, Ian Woods, Sarah F. McComish, Sean Kerr, Matthew McGrath, Juan Carlos Palomeque Chávez, Jack Maughan, Tara McGuire, Maeve A. Caldwell, Adrian Dervan, Fergal J. O'Brien   +10 more
wiley   +1 more source

Hmo1 Promotes Efficient Transcription Elongation by RNA Polymerase I in Saccharomyces cerevisiae. [PDF]

Genes (Basel)
Huffines AK, Schneider DA.
europepmc   +1 more source

Antisense ribosomal siRNAs inhibit RNA polymerase I-directed transcription in C. elegans. [PDF]

Nucleic Acids Res, 2021
Liao S, Chen X, Xu T, Jin Q, Xu Z, Xu D, Zhou X, Zhu C, Guang S, Feng X.   +9 more
europepmc   +1 more source