Results 231 to 240 of about 950,582 (330)

The natural alkaloid nitidine chloride targets RNA polymerase I to inhibit ribosome biogenesis and repress cancer cell growth. [PDF]

Cell Death Discov
Voukeng I, Chen J, Lafontaine DLJ.
europepmc   +1 more source

Generation and characterization of a temperature-sensitive mutant allele of the second largest subunit of RNA polymerase I in Schizosaccharomyces pombe. [PDF]

MicroPubl Biol, 2022
Ishida K, Tanaka K, Kawakami K.
europepmc   +1 more source

Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery

Advanced Healthcare Materials, EarlyView.
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang, Yue Hui, Zichao Guo, Dawei Liu, Yun Liu, Huajian Gao, Chun‐Xia Zhao   +6 more
wiley   +1 more source

Defining the Influence of the A12.2 Subunit on Transcription Elongation and Termination by RNA Polymerase I In Vivo. [PDF]

Genes (Basel), 2021
Clarke AM, Huffines AK, Edwards YJK, Petit CM, Schneider DA.   +4 more
europepmc   +1 more source

Amino acids and control of nucleolar size, the activity of RNA polymerase I, and DNA synthesis in liver.

, 1976
Raymond P. Bailey, Mary Jane Vrooman, Yasuko Sawai, Kinji Tsukada, Susan Short, I Lieberman   +5 more
openalex   +1 more source

Stereochemistry of polymerization by DNA-dependent RNA-polymerase from Escherichia coli: An investigation with a diastereomeric ATP-analogue [PDF]

, 1977

openalex   +1 more source

ROS‐Scavenging Multifunctional Microneedle Patch Facilitating Wound Healing

Advanced Healthcare Materials, EarlyView.
A reactive oxygen species (ROS) scavenging and immunomodulatory microneedle patch based on hyaluronic acid methacrylate (HaMA) and Flightless I (Flii)‐siRNA‐laden arginine functionalized poly (β‐amino ester)/alginate particles is developed for chronic wound healing applications.
Mahshid Kharaziha, Sahar Salehi, Mahshid Shokri, Seyed Mohsen Ahmadi Tafti, Thomas Scheibel   +4 more
wiley   +1 more source

Evolutionary and Structural Insights into the RNA Polymerase I A34 Protein Family: A Focus on Intrinsic Disorder and Phase Separation. [PDF]

Genes (Basel)
Knutson BA, Rothblum LI.
europepmc   +1 more source

RNA polymerase I inhibition induces terminal differentiation, growth arrest, and vulnerability to senolytics in colorectal cancer cells. [PDF]

Mol Oncol, 2022
Otto C, Kastner C, Schmidt S, Uttinger K, Baluapuri A, Denk S, Rosenfeldt MT, Rosenwald A, Roehrig F, Ade CP, Schuelein-Voelk C, Diefenbacher ME, Germer CT, Wolf E, Eilers M, Wiegering A.   +15 more
europepmc   +1 more source

Processive pyrophosphorolysis of RNA by Escherichia coli RNA polymerase [PDF]

, 1982
T. A. Rozovskaya, Alex Chenchik, R. Sh. Beabealashvilli   +2 more
openalex   +1 more source