Results 271 to 280 of about 1,401,767 (284)

Yeast apo RNA polymerase I*

, 2019
RNA polymerase (Pol) I is a 14-subunit enzyme that solely transcribes pre-ribosomal RNA. Cryo-electron microscopy (EM) structures of Pol I initiation and elongation complexes have given first insights into the molecular mechanisms of Pol I transcription.
L. Tafur, Y. Sadian, Jonas Hanske, R. Wetzel, F. Weis, C. Müller   +5 more
semanticscholar   +1 more source

Mechanism of RNA Polymerase I Transcription

2004
Publisher Summary This chapter presents an overview of the RNA polymerase I (Pol I) transcription system, with particular emphasis on the latest findings on the mechanisms that regulate it. Comprehensive reviews on yeast and vertebrate RNA polymerase is also presented.
openaire   +3 more sources

The RNA Polymerase I Transcription Machinery

2011
In this chapter, we review transcription of mammalian rRNA genes by RNA polymerase I (Pol I), a process that integrates information from cellular signaling cascades to regulate ribosome production. Although the emerging picture of Pol I transcriptional regulation reveals an unexpected level of complexity, we are beginning to understand the multiple ...
Ingrid Grummt, Renate Voit
openaire   +2 more sources

Characterization of the RNA polymerases of Crithidia fascicuiata

Molecular Microbiology, 1991
SummaryWe have characterized the crithidial RNA polymerases (RNAPs). The RNAPs from this organism were resolved by chromatography and could be classified into RNAP I, II and III because of their differential sensitivity to class‐specific RNA polymerase inhibitors, such as alpha‐amanitin (ama) and tagetitoxin.
A. W. C. A. Cornelissen, J. Köck
openaire   +3 more sources

In VitroInteractions ofPseudomonasRNA Polymerases withtacand RNA I Promoters

Bioscience, Biotechnology, and Biochemistry, 1992
The activities of RNA polymerases from Pseudomonas putida and Pseudomonas aeruginosa were compared with that of Escherichia coli RNA polymerase in an in vitro transcription system. All three enzymes initiated transcription at the tac promoter and the RNA I promoter of E. coli.
Masaya Fujita, Akinori Amemura
openaire   +3 more sources

RNA polymerases I and III, non-coding RNAs and cancer

Trends in Genetics, 2008
Oncogenically transformed cells overexpress the non-coding RNAs, such as pre-ribosomal RNA (rRNA) and transfer RNA (tRNA), which are produced by RNA polymerases (Pols) I and III. Recent results indicate that levels of pre-rRNA have prognostic value and that a tRNA has oncogenic potential.
openaire   +2 more sources

RNA Polymerase I Transcription [PDF]

, 2014
Ross D. Hannan, Denis Drygin
openaire   +1 more source

Structure of RNA polymerase I transcribing ribosomal DNA genes

Nature, 2016
S. Neyer, Michael Kunz, C. Geiss, M. Hantsche, V. Hodirnau, A. Seybert, C. Engel, M. Scheffer, P. Cramer, A. Frangakis   +9 more
semanticscholar   +1 more source

c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I

Nature Cell Biology, 2005
C. Grandori, N. Gomez-Roman, Zoë A. Felton-Edkins, C. Ngouenet, D. Galloway, R. Eisenman, Robert J White   +6 more
semanticscholar   +1 more source

c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription

Nature Cell Biology, 2005
Azadeh Arabi, Siqin Wu, Karin K. Ridderstråle, Holger Bierhoff, C. Shiue, K. Fátyol, Sara Fahlén, P. Hydbring, O. Söderberg, I. Grummt, L. Larsson, A. Wright   +11 more
semanticscholar   +1 more source