Results 71 to 80 of about 1,401,767 (284)
RNA polymerase I activation and hibernation: unique mechanisms for unique genes
Transcription, 2018 In yeast, transcription of ribosomal DNA (rDNA) by RNA polymerase I (Pol I) is regulated by unique mechanisms acting at the level of the enzyme. Under stress situations such as starvation, Pol I hibernates through dimerization. When growth conditions are
C. Fernández‐Tornero
semanticscholar +1 more source
Witnessing the Evolution of RNA [PDF]
, 2022 The RNA World theory postulates that at a certain point around 4 billion years ago during an RNA World period, a molecule, possibly RNA, developed the ability to self-replicate via polymerization.
Portillo, Xavier
core +1 more source
Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus.
Genes & Development, 2003 Mammalian cells contain 100 or more copies of tandemly repeated ribosomal RNA (rRNA) genes per haploid genome. These genes are transcribed with high efficiency to keep up with the cell’s metabolic activity and demand for ribosomes.
I. Grummt
semanticscholar +1 more source
Memorias do Instituto Oswaldo Cruz, 2012 Trypanosomatidae is a family of early branching eukaryotes harbouring a distinctive repertoire of gene expression strategies. Functional mature messenger RNA is generated via the trans-splicing and polyadenylation processing of constitutively transcribed
Mario Gustavo Mayer +1 more
doaj +1 more source
Viruses, 2020 In this study, we describe the biological function of the phage-encoded protein RNA polymerase alpha subunit cleavage protein (Rac), a predicted Gcn5-related acetyltransferase encoded by phiKMV-like viruses.
Pieter-Jan Ceyssens +13 more
doaj +1 more source
SAF-A Forms a Complex with BRG1 and Both Components Are Required for RNA Polymerase II Mediated Transcription [PDF]
, 2011 Background: Scaffold attachment factor A (SAF-A) participates in the regulation of gene expression by organizing chromatin into transcriptionally active domains and by interacting directly with RNA polymerase II. Methodology: Here we use co-localization,
Runnberg, Rikard +4 more
core +4 more sources
The TyrR protein of Escherichia coli is a class I transcription activator [PDF]
, 1995 The purified TyrR protein and phenylalanine were sufficient to activate in vitro transcription from the tyrP promoter by wild-type RNA polymerase. Such TyrR-mediated activation did not occur when the mutant alpha 235 RNA polymerase was used, indicating ...
A Ishihama +3 more
core +2 more sources
Frontiers in Molecular Biosciences, 2022 The mechanism of remdesivir incorporation into the RNA primer by the RNA-dependent RNA polymerase (RdRp) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) remains to be fully established at the molecular level.
Yuanjun Shi +2 more
doaj +1 more source
SARS-CoV-2 and miRNA-like inhibition power [PDF]
arXiv, 2020 (1) Background: RNA viruses and especially coronaviruses could act inside host cells not only by building their own proteins, but also by perturbing the cell metabolism. We show the possibility of miRNA-like inhibitions by the SARS-CoV-2 concerning for example the hemoglobin and type I interferons syntheses, hence highly perturbing oxygen distribution ...
arxiv
Identification of Five Putative Yeast RNA Helicase Genes [PDF]
, 1990 The RNA helicase gene family encodes a group of eight homologous proteins that share regions of sequence similarity. This group of evolutionarily conserved proteins presumably all utilize ATP (or some other nucleoside triphosphate) as an energy source ...
Abelson, John +2 more
core +1 more source