Results 211 to 220 of about 511,960 (264)

Regulation of RNA polymerase II transcription through re-initiation and bursting. [PDF]

Mol Cell
Nagel M, Taatjes DJ.
europepmc   +1 more source

GLS1-RNA Polymerase II Axis Mediates Glutamine-Dependent Hepatoprotective Effects on Alcoholic Liver Disease in High-Protein Diets. [PDF]

Adv Sci (Weinh)
Wu W, Jiang H, Liu Y, Peng C, Wang H, Yang W, Lyu Z, Sun Y, Ma H, Gu H, Kan W, Jing L, Dong T, Xia C, Lei S, Wu R, Li J, Li J.   +17 more
europepmc   +1 more source

Structural basis of RECQL5-induced RNA polymerase II transcription braking and subsequent reactivation. [PDF]

Nat Struct Mol Biol
Zhang L, Gordiyenko Y, Morgan T, Franco C, Tufegdžić Vidaković A, Zhang S.   +5 more
europepmc   +1 more source

Systems-level feedback loops maintain gene expression homeostasis following RNA polymerase II dosage perturbation

Olthof AM, Noe Gonzalez MJ, Poulsen NB, Moreno NN, Bautu T, Cugusi S, Svejstrup JQ.   +6 more
europepmc   +1 more source

Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5

Sebesta M, Skubnik K, Morton W, Kravec M, Linhartova K, Klapstova V, Novacek J, Kubicek K, Bryja V, Vacha R, Stefl R.   +10 more
europepmc   +1 more source

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RNA Polymerase: Structural Similarities Between Bacterial RNA Polymerase and Eukaryotic RNA Polymerase II

Journal of Molecular Biology, 2000
Bacterial RNA polymerase and eukaryotic RNA polymerase II exhibit striking structural similarities, including similarities in overall structure, relative positions of subunits, relative positions of functional determinants, and structures and folding topologies of subunits.
Richard H Ebright
exaly   +3 more sources

The Mediator of RNA polymerase II

Chromosoma, 2005
Mediator (TRAP/ARC/PC2) is a large (22-28 subunit) protein complex that binds RNA polymerase II and controls transcription from class II genes. The evolutionarily conserved core of Mediator is found in all eukaryotes. It binds RNA polymerase II and is probably critical for basal transcription but it also mediates activation and repression of ...
Erik, Blazek, Gerhard, Mittler, Michael, Meisterernst   +2 more
openaire   +2 more sources

The RNA Polymerase II Elongation Complex

Annual Review of Biochemistry, 1995
▪ Abstract  Synthesis of eukaryotic mRNA by RNA polymerase II is an elaborate biochemical process that requires the concerted action of a large set of transcription factors. RNA polymerase II transcription proceeds through multiple stages designated preinitiation, initiation, and elongation.
T, Aso, J W, Conaway, R C, Conaway
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Tails of RNA polymerase II

Trends in Biochemical Sciences, 1990
Eukaryotic RNA polymerase II contains two distinct structural domains: a catalytic core consisting of subunits that are homologous to other multisubunit RNA polymerases, and a unique extension of the carboxy-terminus of the largest subunit comprising tandem repeats of the seven amino acid sequence YSPTSPS. This repetitive 'tail' domain is essential for
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