Results 231 to 240 of about 616,337 (352)

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Use of multiple 16S rRNA-targeted fluorescent probes to increase signal strength and measure cellular RNA from natural planktonic bacteria

, 1993
S Lee, Camila Francieli Silva Malone, Paul F. Kemp   +2 more
openalex   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

A molecular scaffold for concurrent targeting of plasma and mitochondrial membranes. [PDF]

Chem Sci
Lai Y, Yang Y, Zhao Y, James TD, Lin W.
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Wet Lab Techniques for the Functional Analysis of Circular RNA. [PDF]

Cells
Chakravarthi VP, Christenson LK.
europepmc   +1 more source

Cleavage of tRNA with imidazole and spermine imidazole constructs: a new approach for probing RNA structure

, 1995
Valentin V. Vlassov, Guy Zuber, Brice Felden, Jean‐Paul Behr, Richard Giegé   +4 more
openalex   +2 more sources

Probing the TRAP–RNA interaction with nucleoside analogs [PDF]

, 1999
Matthew B. Elliott, Philip A. Gottlieb, Paul Gollnick   +2 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Transcript-Capture sequencing enriches mRNA of <i>Mycobacterium tuberculosis</i> from host samples. [PDF]

NAR Mol Med
Lamont EI, Jones RM, Assadi J, Morrison R, Song T, Yu X, Weiner DM, Via LE, Winter J, Ma S, Wilkinson RJ, Barry CE, Sherman DR.   +12 more
europepmc   +1 more source