Results 61 to 70 of about 601,872 (302)
Genomics Data, 2016 Malarial parasite P. falciparum, an apicomplexan protozoan has a 23.3 MB nuclear genome and encodes ~5600 transcripts. The genetic diversity of the parasite within and across geographical zones is a challenge to gene expression studies which are ...
Amit Kumar Subudhi +9 more
doaj +1 more source
Developmental regulation of expression of the lactate dehydrogenase (LDH) multigene family during mouse spermatogenesis [PDF]
, 1990 Expression of the Lactate Dehydrogenase (LDH) genes during various stages of spermatogenesis was studied by using a combination of Northern blot analyses and in situ hybridization techniques.
Bellvé, Anthony +6 more
core
The Embryonic Transcriptome Of The Red-Eared Slider Turtle (Trachemys Scripta) [PDF]
, 2013 The bony shell of the turtle is an evolutionary novelty not found in any other group of animals, however, research into its formation has suggested that it has evolved through modification of conserved developmental mechanisms.
Cebra-Thomas, J. +14 more
core +2 more sources
RNA structure probing dash seq [PDF]
Proceedings of the National Academy of Sciences, 2011 RNA constitutes the central conduit for information storage, conveyance, and manipulation in biological systems (1, 2). RNAs encode their critical information at two levels. First, the primary sequence directs protein synthesis and contains simple cis-acting elements that bind regulatory factors and other RNAs.
openaire +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Stable isotope probing: Technical considerations when resolving ¹⁵N-labeled RNA in gradients [PDF]
, 2010 RNA based stable isotope probing (SIP) facilitates the detection and identification of active members of microbial populations that are involved in the assimilation of an isotopically labeled compound.
Addison, Sarah Louise +2 more
core +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Scientific Reports, 2017 Analysis of RNA dynamics and localization at the single-molecule level in living cells has been predominantly achieved by engineering target RNAs with large insertions of tandem repeat sequences that are bound by protein-based or oligonucleotide-based ...
Mingming Chen +7 more
doaj +1 more source
SNP detection in mRNA in living cells using allele specific FRET probes. [PDF]
PLoS ONE, 2013 Live mRNA detection allows real time monitoring of specific transcripts and genetic alterations. The main challenge of live genetic detection is overcoming the high background generated by unbound probes and reaching high level of specificity with ...
Liya Dahan +4 more
doaj +1 more source
SARS-CoV-2 Mutations and Variants May Muddle the Sensitivity of COVID-19 Diagnostic Assays
Microorganisms, 2022 The performance of diagnostic polymerase chain reaction (PCR) assays can be impacted by SARS-CoV-2 variability as this is dependent on the full complementarity between PCR primers/probes and viral target templates.
Mohammad Alkhatib +5 more
doaj +1 more source