Results 211 to 220 of about 442,476 (336)

Characterising processing conditions that artifactually bias human brain tissue transcriptomes. [PDF]

Nat Commun
Yaqubi M, Thomas M, Talbot-Martin J, Mohammadnia A, Allot A, Groh AMR, Fancy N, Papageorgopoulou M, Zhang X, McGarry A, Matthews PM, Petrecca K, Jackson JS, Stratton JA.   +13 more
europepmc   +1 more source

Processing and turn-over of small non-coding RNA OxyS in E. coli & post-transcriptional regulation of RpoS levels by small non-coding RNAs OxyS and DsrA and the Hfq protein in E. coli

, 2010
rpoS mRNA is one of the first target RNA shown to be regulated by at least 3 small noncoding RNAs under various stress conditions. Two out of three sRNAs are involved in the activation of rpoS mRNA translation. By contrast the third sRNA, OxyS has been implicated in the repression of RpoS synthesis.
openaire   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Piezoelectric Surface Charge and Dynamic Stimulation Synergize to Promote Cardiac Myoblast Alignment and Maturation

Advanced Healthcare Materials, EarlyView.
Surface polarization of PVDF films combined with mechanical stimulation generates piezoelectric electrical cues that modulate cardiomyoblast behaviour. Non‐poled and poled PVDF substrates provide distinct electroactive microenvironments influencing cell adhesion, proliferation, and differentiation.
Rafaela M Meira, Sylvie Ribeiro, Senentxu Lanceros‐Mendez, Clarisse Ribeiro   +3 more
wiley   +1 more source

Transcriptomic Responses of Zebrafish Embryos to Environmentally Relevant, Low-Dose (2-Ethylhexyl) Phthalate Exposure at 96-120 hpf. [PDF]

Genes (Basel)
Pais M, McCafferty K, Campos GL, Hardiman G.   +3 more
europepmc   +1 more source

Sprayable Polymer Blends With Short‐Chain Surface Segregation for Preventing Postoperative Abdominal Adhesions

Advanced Healthcare Materials, EarlyView.
Adhesions’ high occurrence rates and high morbidity render them a critical challenge to be addressed. Current prevention methods, such as physical barriers, have many limitations, resulting in inconsistent safety and efficacy. This study demonstrates the potential for sprayable polymeric materials as an adhesion barrier.
Robert J. Morris III, Tejaswi Nori, Alex I. Halpern, Hannah LaPadula, Arthur V. Cresce, Sarah L. Wright, Anthony D. Sandler, Peter Kofinas   +7 more
wiley   +1 more source

Decoding ALS from the tail end of RNA. [PDF]

Cell Genom
Fujioka Y, Ishigaki S.
europepmc   +1 more source

RITS acts in cis to promote RNA interference–mediated transcriptional and post-transcriptional silencing

Nature Genetics, 2004
K. Noma, T. Sugiyama, H. Cam, A. Verdel, M. Zofall, Songtao Jia, D. Moazed, S. Grewal   +7 more
semanticscholar   +1 more source

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

Multilayer Timing of Cardiac Circadian Regulation Informs Prevention and Treatment of Cardiovascular Disease. [PDF]

Vasc Health Risk Manag
Zhu L, Qian B, Zhang X, Hu LL.
europepmc   +1 more source