Results 321 to 330 of about 798,047 (345)

Timing effciency in small-RNA-regulated post-transcriptional processes

Physical Review E, 2020
Gene regulation in a cellular environment is a stochastic phenomenon leading to a large variability in mRNAs and protein numbers that are often produced in bursts. The regulation leading to varied protein dynamics can be ascribed to transcriptional or post-transcriptional mechanisms.
Kuheli Biswas, Anandamohan Ghosh
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Viral RNA in the cytoplasm of SV40-transformed mouse cells: Post-transcriptional processing

Virology, 1976
Abstract The virus-specific RNA present in the cytoplasmic and total cellular RNA of three standard and three flat lines of SV40-transformed mouse cells has been examined. The results using separated strands of the entire viral genome as hybridization probes indicate that extensive processing or selection of viral-specific RNA sequences occurs in ...
Leong, J C, Smith, H S, Goodman, H M
openaire   +3 more sources

Post-transcriptional processing of cellular RNAs in herpes simplex virus-infected cells

Biochemical Society Transactions, 2004
In HSV-1 (herpes simplex virus 1)-infected cells, the UL41 gene product carried with the virion has been shown to mediate the degradation of mRNA, leading to the shut-off of cellular protein synthesis. Analysis of the RNAs accumulating in cells infected with HSV-1 revealed the accumulation of RNAs encoding numerous cellular proteins both associated ...
Bernard Roizman, Audrey Esclatine, Brunella Taddeo   +2 more
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Post-transcriptional addition of polyadenylic acid to mitochondrial RNA by a cordycepin-insensitive process

Journal of Molecular Biology, 1974
Abstract An RNA fraction in HeLa cell mitochondria has previously been shown to contain a small polyadenylic acid sequence (56 nucleotides) and to behave like messenger RNA. This fraction can be resolved into approximately eight distinct species which may be the messages for the mitochondrial-specified proteins.
Martin Hirsch, Sheldon Penman
openaire   +3 more sources

Abstract 2443: APOBEC3G is a sex-specific determinant of post-transcriptional RNA processing and survival in diffuse large B-cell lymphoma

Cancer Research, 2021
Abstract APOBEC3G is a cytidine deaminase with a well-characterized anti-viral role against HIV and other retroviruses. Its deaminase activity yields G to A edits in ssDNA to disrupt viral coding sequences and inhibits cDNA production during reverse transcription.
Henry Yang, Joanna D. Wardyn, Gene W. Yeo, Omer An, Dominic P. Sheng, Reuben S. Harris, Michal Marek Hoppe, Allison S. Y. Chan, Jia Li, Daniel J. Hodson, Shruthi Venguidessane, Anand D. Jeyasekharan   +11 more
openaire   +2 more sources

The role of post-transcriptional RNA processing and plasmid vector sequences on transient transgene expression in zebrafish

Transgenic Research, 2009
A tissue-specific transgenic model was employed to test the effects of intron and vector sequences on transgene expression in zebrafish after microinjection. In this model, the 2.3 kb promoter taken from the 5' upstream region of the transcription initiation site of keratin 4 (krt4) was used to drive the enhanced green fluorescence protein (EGFP ...
Sumantra Chatterjee, Sumantra Chatterjee, Thomas Lufkin, Thomas Lufkin, Lin Min, R. Krishna Murthy Karuturi   +5 more
openaire   +3 more sources

RNA processing is involved in the post-transcriptional control of the citQRP operon from Lactococcus lactis biovar diacetylactis

Molecular and General Genetics MGG, 1998
The importance of Lactococcus lactis biovar diacetylactis (L. diacetylactis) in the dairy industry is due to its ability to produce aroma compounds, such as acetoin and diacetyl, from citrate. The first step in citrate utilization is its uptake by the cells. In L. diacetylactis, the citrate transport system is encoded by the citQRP operon.
Djamel Drider, Paloma López, Cecília M. Arraiano, Jorge M. Santos   +3 more
openaire   +3 more sources

Theoretical model for the post-transcriptional regulation of the human c-myc gene expression, involving double-stranded RNA processing

Journal of Theoretical Biology, 1987
We propose that the human c-myc gene expression is regulated by a post-transcriptional mechanism based on the formation of a hairpin structure between c-myc mRNA exons 1 and 2. This structure could be rapidly processed by a hypothetical double stranded RNAse, removing the 5' end segment of the c-myc mRNA having the cap site.
Patricio Gariglio, Rosamaria Del Angel, Alfredo Herrera, Manuel Bonilla   +3 more
openaire   +3 more sources

The post-transcriptional life of mammalian mitochondrial RNA.

Biochemical Journal, 2012
Mammalian mitochondria contain their own genome that encodes mRNAs for thirteen essential subunits of the complexes performing oxidative phosphorylation as well as the RNA components (two rRNAs and 22 tRNAs) needed for their translation in mitochondria ...
J. Rorbach, M. Minczuk
semanticscholar   +1 more source

Gene expression control by selective RNA processing and stabilization in bacteria.

FEMS Microbiology Letters, 2013
RNA maturation is a key event regulating genes at post-transcriptional level. In bacteria, it is employed to adjust the amounts of proteins and functional RNAs, often in response to environmental constraints. During the process of RNA maturation, enzymes
T. Rochat, P. Bouloc, F. Repoila
semanticscholar   +1 more source