Results 221 to 230 of about 19,175,801 (290)

Cytoplasmic processing of myosin heavy chain messenger RNA: evidence provided by using a recombinant DNA plasmid.

, 1980
Russell M. Medford, Robert Wydro, Hanh T. Nguyen, B Nadal-Ginard   +3 more
openalex   +2 more sources

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

High resolution landscape of ribosomal RNA processing and surveillance. [PDF]

Nucleic Acids Res
An W, Yan Y, Ye K.
europepmc   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration.

Human Molecular Genetics, 2010
C. Lagier-Tourenne, M. Polymenidou, D. Cleveland   +2 more
semanticscholar   +1 more source

Tiny Molecular Beacons: LNA/2′-O-methyl RNA Chimeric Probes for Imaging Dynamic mRNA Processes in Living Cells

, 2012
Irina E. Catrina, Salvatore A. E. Marras, Diana P. Bratu   +2 more
openalex   +2 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

RNA exosome-driven RNA processing instructs the duration of the unfolded protein response. [PDF]

Nucleic Acids Res
Matabishi-Bibi L, Goncalves C, Babour A.
europepmc   +1 more source

RNA-Methylation-Dependent RNA Processing Controls the Speed of the Circadian Clock

Cell, 2013
J. Fustin, M. Doi, Y. Yamaguchi, H. Hida, S. Nishimura, Minoru Yoshida, T. Isagawa, M. Morioka, H. Kakeya, I. Manabe, H. Okamura   +10 more
semanticscholar   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source