Results 51 to 60 of about 10,995,303 (306)
Influence of genome-scale RNA structure disruption on the replication of murine norovirus--similar replication kinetics in cell culture but attenuation of viral fitness in vivo [PDF]
, 2013 Mechanisms by which certain RNA viruses, such as hepatitis C virus, establish persistent infections and cause chronic disease are of fundamental importance in viral pathogenesis.
Evans, David J +9 more
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Review of machine learning methods for RNA secondary structure prediction.
PLoS Computational Biology, 2021 Secondary structure plays an important role in determining the function of noncoding RNAs. Hence, identifying RNA secondary structures is of great value to research. Computational prediction is a mainstream approach for predicting RNA secondary structure.
Qi Zhao +5 more
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Shape based indexing for faster search of RNA family databases [PDF]
, 2008 Janssen S, Reeder J, Giegerich R. Shape based indexing for faster search of RNA family databases. BMC Bioinformatics. 2008;9(1):131.Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure.
Janssen Stefan +5 more
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Probing the Structures of Viral RNA Regulatory Elements with SHAPE and Related Methodologies
Frontiers in Microbiology, 2018 Viral RNAs were selected by evolution to possess maximum functionality in a minimal sequence. Depending on the classification of the virus and the type of RNA in question, viral RNAs must alternately be replicated, spliced, transcribed, transported from ...
Jason W. Rausch +3 more
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Spaces of RNA Secondary Structures
Advances in Mathematics, 1993 The primary goal of the authors is to contribute to investigations of the secondary structure of RNA. The starting point are bond pictures that give rise to partially ordered sets of macromolecules. For such posets corresponding to classes of ``arbitrary'' and ``binary'' macromolecules (the latter being motivated by the study of secondary structures of
Penner, R.C., Waterman, M.S.
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Fine-tuning structural RNA alignments in the twilight zone [PDF]
, 2010 Bremges A, Schirmer S, Giegerich R. Fine-tuning structural RNA alignments in the twilight zone. BMC Bioinformatics. 2010;11(1): 222.Background A widely used method to find conserved secondary structure in RNA is to first construct a multiple sequence ...
Bremges Andreas +8 more
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, 2004 Giegerich R, Voss B, Rehmsmeier M. Abstract shapes of RNA. Nucleic Acids Research. 2004;32(16):4843-4851.The function of a non-protein-coding RNA is often determined by its structure.
Rehmsmeier, Marc +3 more
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Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics [PDF]
, 2004 Reeder J, Giegerich R. Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics. BMC Bioinformatics. 2004;5(1): 104.Background: The general problem of RNA secondary structure prediction under the widely ...
Reeder Jens +5 more
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Shengwu huaxue yu shengwu wuli jinzhanObjectiveNon-coding RNA (ncRNA) plays a crucial regulatory role in various biological processes. Numerous studies have shown that the functions of ncRNAs depend not only on their nucleotide sequences but also closely on their spatial conformations ...
HAO Ze-Zhou +3 more
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Mutational patterns in RNA secondary structure evolution examined in three RNA families. [PDF]
PLoS ONE, 2011 The goal of this work was to study mutational patterns in the evolution of RNA secondary structure. We analyzed bacterial tmRNA, RNaseP and eukaryotic telomerase RNA secondary structures, mapping structural variability onto phylogenetic trees constructed
Anuj Srivastava +3 more
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