Results 61 to 70 of about 10,995,303 (306)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
An algebraic language for RNA pseudoknots comparison
BMC Bioinformatics, 2019 Background RNA secondary structure comparison is a fundamental task for several studies, among which are RNA structure prediction and evolution. The comparison can currently be done efficiently only for pseudoknot-free structures due to their inherent ...
Michela Quadrini +2 more
doaj +1 more source
Viruses, 2023 The function of RNAs is determined by their structure. However, studying the relationship between RNA structure and function often requires altering RNA sequences to modify the structures, which leads to the neglect of the importance of RNA sequences ...
Yuxin Nie, Yuhong Zhang, Jian Wu
doaj +1 more source
Folding and Finding RNA Secondary Structure [PDF]
Cold Spring Harbor Perspectives in Biology, 2010 Optimal exploitation of the expanding database of sequences requires rapid finding and folding of RNAs. Methods are reviewed that automate folding and discovery of RNAs with algorithms that couple thermodynamics with chemical mapping, NMR, and/or sequence comparison.
David H, Mathews +2 more
openaire +2 more sources
Algorithms for RNA secondary structure analysis : prediction of pseudoknots and the consensus shapes approach [PDF]
, 2007 Reeder J. Algorithms for RNA secondary structure analysis : prediction of pseudoknots and the consensus shapes approach. Bielefeld (Germany): Bielefeld University; 2007.Our understanding of the role of RNA has undergone a major change in the last decade.
Reeder, Jens
core
XML schemas for common bioinformatic data types and their application in workflow systems [PDF]
, 2006 Seibel PN, Krüger J, Hartmeier S, et al. XML schemas for common bioinformatic data types and their application in workflow systems. BMC Bioinformatics.
Krüger, Jan +32 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Efficient Generation of RNA Secondary Structure Prediction Algorithm Under PAR Framework
Frontiers in Plant Science, 2022 Prediction of RNA secondary structure is an important part of bioinformatics genomics research. Mastering RNA secondary structure can help us to better analyze protein synthesis, cell differentiation, metabolism, and genetic processes and thus reveal the
Haihe Shi, Xiaoqian Jing
doaj +1 more source
Secondary Structure of Vertebrate Telomerase RNA [PDF]
Cell, 2000 Telomerase is a ribonucleoprotein enzyme that maintains telomere length by adding telomeric sequence repeats onto chromosome ends. The essential RNA component of telomerase provides the template for telomeric repeat synthesis. To determine the secondary structure of vertebrate telomerase RNA, 32 new telomerase RNA genes were cloned and sequenced from a
Greider, Carol W. +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source