Results 51 to 60 of about 1,674,122 (352)

Specific and non specific hybridization of oligonucleotide probes on microarrays [PDF]

open access: yes, 2005
Gene expression analysis by means of microarrays is based on the sequence specific binding of mRNA to DNA oligonucleotide probes and its measurement using fluorescent labels. The binding of RNA fragments involving other sequences than the intended target
Binder, Hans, Preibisch, Stephan
core   +3 more sources

Discovery of RNA secondary structural motifs using sequence-ordered thermodynamic stability and comparative sequence analysis

open access: yesMethodsX, 2023
Major advances in RNA secondary structural motif prediction have been achieved in the last few years; however, few methods harness the predictive power of multiple approaches to deliver in-depth characterizations of local RNA motifs and their potential ...
Jake M. Peterson   +4 more
doaj  

A Beginner’s Guide to Analysis of RNA Sequencing Data [PDF]

open access: yesAmerican Journal of Respiratory Cell and Molecular Biology, 2018
Since the first publications coining the term RNA-seq (RNA sequencing) appeared in 2008, the number of publications containing RNA-seq data has grown exponentially, hitting an all-time high of 2,808 publications in 2016 (PubMed). With this wealth of RNA-seq data being generated, it is a challenge to extract maximal meaning from these datasets, and ...
Elizabeth T. Bartom   +6 more
openaire   +3 more sources

Heteroduplex analysis of the RNA of clone 3 Moloney murine sarcoma virus [PDF]

open access: yes, 1979
Heteroduplex analysis of the RNA isolated from purified virions of clone 3 Moloney murine sarcoma virus (M-MSV) hybridized to cDNA's from Moloney murine leukemia virus (M-MLV) and clone 124 M-MSV shows that the main physical component of clone 3 RNA is ...
Chen, Yueh-Hsiu   +3 more
core  

Structural Alignment of RNAs Using Profile-csHMMs and Its Application to RNA Homology Search: Overview and New Results [PDF]

open access: yes, 2008
Systematic research on noncoding RNAs (ncRNAs) has revealed that many ncRNAs are actively involved in various biological networks. Therefore, in order to fully understand the mechanisms of these networks, it is crucial to understand the roles of ncRNAs ...
Vaidyanathan, P. P., Yoon, Byung-Jun
core   +2 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Encryption of Stereo Image Based on Fractional Chaotic System and RNA Encoding

open access: yesTaiyuan Ligong Daxue xuebao, 2021
For the increasingly wide usage of stereo images, a stereo image encryption algorithm based on fractional-order hyper-chaotic system and dynamic Ribonucleic Acid (RNA) encoding was proposed. In the chaotic sequence generation stage, SHA-256 hash function
Zhenyu LI   +3 more
doaj   +1 more source

Streamlining Quantitative Analysis of Long RNA Sequencing Reads [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Transcriptome analyses allow for linking RNA expression profiles to cellular pathways and phenotypes. Despite improvements in sequencing methodology, whole transcriptome analyses are still tedious, especially for methodologies producing long reads. Currently, available data analysis software often lacks cost- and time-efficient workflows.
Sebastian Oeck   +3 more
openaire   +5 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

A computational method for estimating the PCR duplication rate in DNA and RNA-seq experiments. [PDF]

open access: yes, 2017
BackgroundPCR amplification is an important step in the preparation of DNA sequencing libraries prior to high-throughput sequencing. PCR amplification introduces redundant reads in the sequence data and estimating the PCR duplication rate is important to
Bansal, Vikas
core   +2 more sources

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