Results 41 to 50 of about 2,532,976 (299)

Expanding the repertoire of human tandem repeat RNA-binding proteins.

PLoS ONE, 2023
Protein regions consisting of arrays of tandem repeats are known to bind other molecular partners, including nucleic acid molecules. Although the interactions between repeat proteins and DNA are already widely explored, studies characterising tandem ...
Agustín Ormazábal, Matías Sebastián Carletti, Tadeo Enrique Saldaño, Martín Gonzalez Buitron, Julia Marchetti, Nicolas Palopoli, Alex Bateman   +6 more
doaj   +1 more source

Statistical Design and Analysis of RNA Sequencing Data [PDF]

Genetics, 2010
Abstract Next-generation sequencing technologies are quickly becoming the preferred approach for characterizing and quantifying entire genomes. Even though data produced from these technologies are proving to be the most informative of any thus far, very little attention has been paid to fundamental design aspects of data collection ...
Paul L, Auer, R W, Doerge
openaire   +2 more sources

Electroacupuncture Regulates Mitochondria-Endoplasmic Reticulum interactions via Fn1 in a Parkinson’s Disease Model: Transcriptomic Evidence

Journal of Integrative Neuroscience
Aims: Parkinson’s disease (PD) is characterized by dopaminergic neuron degeneration and disruption to mitochondria-associated endoplasmic reticulum membranes (MAMs).
Peilin Lyu, Feng Wen, Zhiyi Fu, Junying Li, Qiyan Li, Xiaowen Cai, Shengtao Huang, Xiaoke Qiu, Zhinan Zhang, Yong Huang, Jiping Zhang   +10 more
doaj   +1 more source

RNA sequence analysis of a perinatal lethal osteogenesis imperfecta mutation.

Journal of Biological Chemistry, 1989
The perinatal lethal form of osteogenesis imperfecta often results from mutations which disrupt stable assembly, delay secretion, and cause excessive posttranslational modification of type I procollagen molecules.
E. Patterson, E. Smiley, J. Bonadio
semanticscholar   +1 more source

A Low Sodium Diet Activates HSD2 Neurons in the Nucleus Tractus Solitarii to Promote Sodium Appetite Via the cAMP/MAPK Signaling Pathway

Journal of Integrative Neuroscience
Background: Sodium homeostasis is crucial for physiological balance, yet the neurobiological mechanisms underlying sodium appetite remain incompletely understood.
Xue Zhao, Yongqiang Chen, Ke Zhao, Yanxuan Wei, Yongan Zhang, Kun Liu, Luo Shi   +6 more
doaj   +1 more source

The First Complete Genome Sequence of a Novel Tetrastichus brontispae RNA Virus-1 (TbRV-1)

Viruses, 2019
The complete sequence of a novel RNA virus isolated from Tetrastichus brontispae (TbRV-1) was determined to be 12,239 nucleotides in length with five non-overlapping, linearly arranged coding sequences (CDS), potentially encoding nucleoproteins ...
E Meng, Baozhen Tang, Francisco Javier Sanchez-Garcia, Ting Qiao, Lang Fu, Yu Wang, You-Ming Hou, Jiang-Lin Wu, Zhi-Ming Chen   +8 more
doaj   +1 more source

Whole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to Mycobacterium bovis infection in vitro

BMC Genomics, 2013
BackgroundMycobacterium bovis, the causative agent of bovine tuberculosis, is an intracellular pathogen that can persist inside host macrophages during infection via a diverse range of mechanisms that subvert the host immune response.
N. Nalpas, Stephen D. E. Park, D. A. Magee, M. Taraktsoglou, J. Browne, K. Conlon, Kevin C. Rue-Albrecht, K. Killick, K. Hokamp, A. Lohan, B. Loftus, E. Gormley, S. Gordon, D. MacHugh   +13 more
semanticscholar   +1 more source

Intelligent deep analysis of DNA sequences based on FFGM to enhancement the performance and reduce the computation

Egyptian Informatics Journal, 2023
In an attempt to improve the analysis DNA sequence, a new intelligent deep analysis algorithm called reduce frequency bast on fast frequency graph mining (RF-FFGM) is established; This algorithm at the beginning converts the DNA sequence into RNA ...
Zena A. Kadhuim, Samaher Al-Janabi
doaj   +1 more source

SILVA: a comprehensive online resource for quality checked and aligned ribosomal RNA sequence data compatible with ARB

Nucleic Acids Research, 2007
Sequencing ribosomal RNA (rRNA) genes is currently the method of choice for phylogenetic reconstruction, nucleic acid based detection and quantification of microbial diversity. The ARB software suite with its corresponding rRNA datasets has been accepted
Elmar Pruesse, C. Quast, K. Knittel, B. Fuchs, W. Ludwig, J. Peplies, F. Glöckner   +6 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source