Results 21 to 30 of about 1,335,933 (257)

Next generation sequencing for studying viruses and RNA silencing-based antiviral defense in crop plants [PDF]

open access: yes, 2014
The main objectives of this work have been to use next generation sequencing (NGS) and develop bioinformatics tools for plant virus diagnostics and genome reconstruction as well as for investigation of RNA silencing-based antiviral defense.
Seguin, Jonathan
core   +1 more source

Development of methods for the analysis of deep sequencing data; applications to the discovery of functions of RNA-binding proteins [PDF]

open access: yes, 2014
With the recent advances in nucleotide sequencing technologies, it became easy to generate tens of millions of reads with genome- or transcriptome-wide distribution with reduced cost and high accuracy.
Bilen, Biter
core   +1 more source

Small RNA transcriptome analysis using parallel single-cell small RNA sequencing

open access: yesScientific Reports, 2023
miRNA and other forms of small RNAs are known to regulate many biological processes. Single-cell small RNA sequencing can be used to profile small RNAs of individual cells; however, limitations of efficiency and scale prevent its widespread application ...
Jia Li   +4 more
doaj   +1 more source

Integrative analysis revealed the molecular mechanism underlying RBM10‐mediated splicing regulation

open access: yesEMBO Molecular Medicine, 2013
RBM10 encodes an RNA binding protein. Mutations in RBM10 are known to cause multiple congenital anomaly syndrome in male humans, the TARP syndrome. However, the molecular function of RBM10 is unknown.
Yongbo Wang   +14 more
doaj   +1 more source

Clinical Perspectives of Single-Cell RNA Sequencing

open access: yesBiomolecules, 2021
The ability of single-cell genomics to resolve cellular heterogeneity is highly appreciated in cancer and is being exploited for precision medicine. In the recent decade, we have witnessed the incorporation of cancer genomics into the clinical decision ...
Nayoung Kim, Hye Hyeon Eum, Hae-Ock Lee
doaj   +1 more source

Metagenomes, metatranscriptomes and microbiomes of naturally decomposing deadwood

open access: yesScientific Data, 2021
Measurement(s) metagenomic data • metatranscriptomic data • microbiome • RNA-seq of total RNA Technology Type(s) DNA sequencing • RNA-seq of total RNA • amplicon sequencing • RNA sequencing Factor Type(s) time of decomposition Sample Characteristic ...
Vojtěch Tláskal   +7 more
doaj   +1 more source

Comparative analysis of RNA enrichment methods for preparation of Cryptococcus neoformans RNA sequencing libraries

open access: yesG3: Genes, Genomes, Genetics, 2021
RNA sequencing (RNA-Seq) experiments focused on gene expression involve removal of ribosomal RNA (rRNA) because it is the major RNA constituent of cells.
Calla L Telzrow   +7 more
doaj   +1 more source

Integrated proteome sequencing, bulk RNA sequencing and single-cell RNA sequencing to identify potential biomarkers in different grades of intervertebral disc degeneration

open access: yesFrontiers in Cell and Developmental Biology, 2023
Low back pain (LBP) is a prevalent health problem worldwide that affects over 80% of adults during their lifetime. Intervertebral disc degeneration (IDD) is a well-recognized leading cause of LBP.
Xiao Yang   +4 more
doaj   +1 more source

Computational analysis of next generation sequencing data : from transcription start sites in bacteria to human non-coding RNAS [PDF]

open access: yes, 2014
The advent of next generation sequencing (NGS) technologies has revolutionized the field of molecular biology by providing a wealth of sequence data. “Transcriptomics”, which aims to identify and annotate the complete set of RNA molecules transcribed ...
Jorjani, Hadi
core   +1 more source

RNA-sequencing dataset

open access: yes, 2022
RNA-sequencing dataset generated in the study, "A ubiquitination cascade regulating the integrated stress response and survival in carcinomas."
Cervia (13999059)
core   +1 more source

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