Results 11 to 20 of about 1,733,662 (377)
Suppression of RNA silencing by a plant DNA virus satellite requires a host calmodulin-like protein to repress RDR6 expression. [PDF]
PLoS Pathogens, 2014 In plants, RNA silencing plays a key role in antiviral defense. To counteract host defense, plant viruses encode viral suppressors of RNA silencing (VSRs) that target different effector molecules in the RNA silencing pathway.
Fangfang Li +3 more
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RNA silencing sheds light on the RNA world. [PDF]
PLoS Biology, 2006 RNA silencing — also known as RNA interference — is an intriguing phenomenon in which short, double-stranded RNA “triggers” can prevent the expression of specific genes. First discovered in plants, RNA interference is now recognized as a widespread, if not ubiquitous, phenomenon, and it is causing great excitement as an experimental technique for ...
Rachel Jones
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Nature, 2002 Our cells have a built-in mechanism for 'silencing' genes, called RNA interference. This capability has now been exploited to protect cells in culture dishes from HIV-1 and poliovirus.
Gordon Carmichael
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Dicer dependent tRNA derived small RNAs promote nascent RNA silencing
Nucleic Acids Research, 2022 In mammalian cells, small non-coding RNAs (sncRNAs) negatively regulate gene expression in a pathway known as RNA interference (RNAi). RNAi can be categorized into post-transcriptional gene silencing (PTGS), which involves the cleavage of target ...
Arianna Di Fazio +4 more
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The Role of Viruses in Identifying and Analyzing RNA Silencing.
Annual Review of Virology, 2022 Adaptive antiviral immunity in plants is an RNA-based mechanism in which small RNAs derived from both strands of the viral RNA are guides for an Argonaute (AGO) nuclease. The primed AGO specifically targets and silences the viral RNA.
D. Baulcombe
semanticscholar +1 more source
Non-Coding RNA, 2021 RNA silencing pathways control eukaryotic gene expression transcriptionally or posttranscriptionally in a sequence-specific manner. In RNA silencing, the production of double-stranded RNA (dsRNA) gives rise to various classes of 20–24 nucleotide (nt ...
Xia Hua +5 more
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Current Biology, 2007 PIWI-interacting RNAs (piRNAs), 24–30 nucleotide long RNAs found in the germ cells of animals, are unique among small silencing RNAs in that they require neither an RdRP nor Dicer for their production (Figure 1Figure 1C). Instead, they are thought to derive from single-stranded precursor RNAs tens or hundreds of thousands of nucleotides long.
Christian B. Matranga, Phillip D. Zamore
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RNA Silencing and the Mobile Silencing Signal [PDF]
The Plant Cell, 2002 RNA silencing is a sequence-specific RNA degradation mechanism that occurs in a broad range of eukaryotic organisms including fungi (quelling), animals (RNA interference [RNAi]), and plants (post-transcriptional gene silencing).
Gail J. Pruss +7 more
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Fungal Virus, FgHV1-Encoded p20 Suppresses RNA Silencing through Single-Strand Small RNA Binding
Journal of Fungi, 2022 Fungal viruses are widespread in fungi infecting plants, insects and animals. High-throughput sequencing has rapidly led to the discovery of fungal viruses. However, the interactive exploration between fungi and viruses is relatively limited.
Shuangchao Wang +5 more
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RNA silencing in Monterey [PDF]
Development, 2011 The tenth annual Keystone Symposium on the Mechanism and Biology of Silencing convened in Monterey, California, in March 2011. Those seeking some West Coast sunshine were, unfortunately, met with incessant precipitation throughout the meeting. Nevertheless, attendees were brightened by enlightening and vigorous scientific discussions.
Olivia S. Rissland, Eric C. Lai
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