Results 21 to 30 of about 1,733,662 (377)
RNA silencing in Drosophila [PDF]
Knowledge of the role of RNA in affecting gene expression has expanded in the past several years. Small RNAs serve as homology guides to target messenger RNAs for destruction at the post‐transcriptional level in the experimental technique known as RNA interference and in the silencing of some transgenes.
Weiwu Xie+3 more
openaire +3 more sources
The VP3 factor from viruses of Birnaviridae family suppresses RNA silencing by binding both long and small RNA duplexes. [PDF]
RNA silencing is directly involved in antiviral defense in a wide variety of eukaryotic organisms, including plants, fungi, invertebrates, and presumably vertebrate animals.
Adrian Valli+6 more
doaj +1 more source
The Piwi-interacting RNA (piRNA) pathway plays an essential role in the repression of transposons in the germline. Other functions of piRNAs such as post-transcriptional regulation of mRNAs are now emerging.
Bridlin Barckmann+11 more
doaj +1 more source
RNA silencing is a common antiviral mechanism in eukaryotic organisms. However, the transcriptional regulatory mechanism that controls the RNA silencing process remains elusive.
Yingru Xu+9 more
doaj +1 more source
RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure [PDF]
Selective gene silencing by RNA interference (RNAi) involves double-stranded small interfering RNA (ds siRNA) composed of single-stranded (ss) guide and passenger RNAs.
Ahmed+38 more
core +6 more sources
RNA Silencing and Plant Viral Diseases
RNA silencing plays a critical role in plant resistance against viruses, with multiple silencing factors participating in antiviral defense. Both RNA and DNA viruses are targeted by the small RNA-directed RNA degradation pathway, with DNA viruses being ...
Ming-Bo Wang+3 more
doaj +1 more source
Mechanisms of resistance to viruses
Resistance associated with a hypersensitive response (HR) and subsequent development of necrotic lesions (cell death) at the sites of virus infection can restrict virus movement in plants. Genes for HR are dominant and act on a gene-for-gene basis.
J.P.T. Valkonen
doaj +1 more source
Secondary siRNAs in Plants: Biosynthesis, Various Functions, and Applications in Virology
The major components of RNA silencing include both transitive and systemic small RNAs, which are technically called secondary sRNAs. Double-stranded RNAs trigger systemic silencing pathways to negatively regulate gene expression.
Neeti Sanan-Mishra+4 more
doaj +1 more source
A petunia ethylene-responsive element binding factor, PhERF2, plays an important role in antiviral RNA silencing. [PDF]
Virus-induced RNA silencing is involved in plant antiviral defense and requires key enzyme components, including RNA-dependent RNA polymerases (RDRs), Dicer-like RNase III enzymes (DCLs), and Argonaute proteins (AGOs).
Jiang, Cai-Zhong+5 more
core +1 more source
RNA silencing platforms in plants [PDF]
Since the discovery of RNAi, its mechanism in plants and animals has been intensively studied, widely exploited as a research tool, and used for a number of potential commercial applications. In this article, we discuss the platforms for delivering RNAi in plants.
Watson, John+3 more
openaire +4 more sources