Results 291 to 300 of about 1,673,511 (373)

Deficiency of multiple RNA silencing-associated genes may contribute to the increased susceptibility of Nicotiana benthamiana to viruses. [PDF]

Plant Cell Rep
Ludman M, Anita S, Fátyol K.
europepmc   +1 more source

RNA Interference, Transposon Silencing, and Cosuppression in the Caenorhabditis elegans Germ Line: Similarities and Differences [PDF]

, 2004
Valérie Robert, Nadine L. Vastenhouw, Ronald H.A. Plasterk   +2 more
openalex   +1 more source

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

Advanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong, Shanshan Dai, Fan Yu, Guo‐Ping Shi, Qinyan Gong, Yucong Zhang, Jingsi Duan, Zhengyin Lou, Zhixuan Tang, Fuzhe Gong, Derong Chen, Liya Hou, Xinyang Hu, Jinghai Chen, Jian'an Wang, Deling Yin   +15 more
wiley   +1 more source

Single-base tiled screen unveils design principles of PspCas13b for potent and off-target-free RNA silencing. [PDF]

Nat Struct Mol Biol
Hu W, Kumar A, Ahmed SF, Qi S, Ma DKG, Chen H, Singh GJ, Casan JML, Haber M, Voskoboinik I, McKay MR, Trapani JA, Ekert PG, Fareh M.   +13 more
europepmc   +1 more source

Faculty Opinions recommendation of Inducible systemic RNA silencing in Caenorhabditis elegans.

, 2003
Oliver Hobert
openalex   +2 more sources

RITS acts in cis to promote RNA interference–mediated transcriptional and post-transcriptional silencing [PDF]

, 2004
Ken-ichi Noma, Tomoyasu Sugiyama, Hugh P. Cam, André Verdel, Martin Zofall, Songtao Jia, Danesh Moazed, Shiv I. S. Grewal   +7 more
openalex   +1 more source

Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation

Advanced Science, EarlyView.
Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu, Tong Ji, Zhichao Ye, Jianing Yan, Chao Wang, Jiachen Chen, Ziyang Jin, Yongji Zhu, Xiujun Cai, Yifan Wang   +9 more
wiley   +1 more source

Withdrawal: RNA Silencing Identifies PDE4D5 as the Functionally Relevant cAMP Phosphodiesterase Interacting with βArrestin to Control the Protein Kinase A/AKAP79-mediated Switching of the β₂-Adrenergic Receptor to Activation of ERK in HEK293B2 Cells. [PDF]

J Biol Chem
Lynch MJ, Baillie GS, Mohamed A, Li X, Maisonneuve C, Klussmann E, van Heeke G, Houslay MD.   +7 more
europepmc   +1 more source

Faculty Opinions recommendation of The presence of a chromatin boundary appears to shield a transgene in tobacco from RNA silencing.

, 2003
Eric Lam
openalex   +2 more sources

Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: Enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition [PDF]

, 2004
Dong Wang, Meihua Luo, Mark R. Kelley
openalex   +1 more source