Statistical Tests for Detecting Differential RNA-Transcript Expression from Read Counts [PDF]
, 2010 As a fruit of the current revolution in sequencing technology, transcriptomes can now be analyzed at an unprecedented level of detail. These advances have been exploited for detecting differential expressed genes across biological samples and for ...
Gunnar Rätsch +5 more
core +2 more sources
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
RNA Unwinding by the Trf4/Air2/Mtr4 Polyadenylation (TRAMP) Complex [PDF]
, 2012 Many RNA-processing events in the cell nucleus involve the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex, which contains the poly(A) polymerase Trf4p, the Zn-knuckle protein Air2p, and the RNA helicase Mtr4p.
Anderson, James T. +3 more
core +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
The Prediction of Tertiary Structure of RNA Based upon Secondary Structure by Using the Relaxation Method and Texture Mapping Method [PDF]
Journal of Systemics, Cybernetics and Informatics, 2013 In this paper, we propose a method to predict tertiary structure of an RNA sequence. Our prediction method would first find the secondary structure of the given RNA sequence.
C.C. Lin, R.C.T. Lee
doaj
RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme
RNA: A publication of the RNA Society, 2017 RNA-Puzzles is a collective experiment in blind 3D RNA structure prediction. We report here a third round of RNA-Puzzles. Five puzzles, 4, 8, 12, 13, 14, all structures of riboswitch aptamers and puzzle 7, a ribozyme structure, are included in this round
Zhichao Miao +45 more
semanticscholar +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Structure-seq2: sensitive and accurate genome-wide profiling of RNA structure in vivo
Nucleic Acids Research, 2017 RNA serves many functions in biology such as splicing, temperature sensing, and innate immunity. These functions are often determined by the structure of RNA.
Laura E. Ritchey +5 more
semanticscholar +1 more source
RNA Motifs and Modification Involve in RNA Long-Distance Transport in Plants
Frontiers in Cell and Developmental Biology, 2021 A large number of RNA molecules have been found in the phloem of higher plants, and they can be transported to distant organelles through the phloem.
Tao Wang +10 more
doaj +1 more source
On Topological RNA Interaction Structures [PDF]
Journal of Computational Biology, 2013 Recently a folding algorithm of topological RNA pseudoknot structures was presented in Reidys et al. (2011). This algorithm folds single-stranded γ-structures, that is, RNA structures composed by distinct motifs of bounded topological genus. In this article, we set the theoretical foundations for the folding of the two backbone analogues of γ ...
Qin, Jing, Reidys, Christian
openaire +3 more sources