Results 51 to 60 of about 15,140,513 (376)
RNApolis: Computational Platform for RNA Structure Analysis
Foundations of Computing and Decision Sciences, 2019 In the 1970s, computer scientists began to engage in research in the field of structural biology. The first structural databases, as well as models and methods supporting the analysis of biomolecule structures, started to be created.
Szachniuk Marta
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A small RNA response at DNA ends in Drosophila [PDF]
, 2012 Small RNAs have been implicated in numerous cellular processes, including effects on chromatin structure and the repression of transposons. We describe the generation of a small RNA response at DNA ends in Drosophila that is analogous to the recently ...
Böttcher, Romy +2 more
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Nature Communications, 2018 The mitochondrial RNA degradosome (mtEXO) plays an essential role in the regulation of mitochondrial gene expression and is composed of the 3′-to-5′ exoribonuclease Dss1 and the helicase Suv3.
Michal Razew +12 more
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bioRxiv, 2020 Due to the mounting evidence that RNA structure plays a critical role in regulating almost any physiological as well as pathological process, being able to accurately define the folding of RNA molecules within living cells has become a crucial need.
Tycho Marinus +3 more
semanticscholar +1 more source
Helix capping in RNA structure. [PDF]
PLoS ONE, 2014 Helices are an essential element in defining the three-dimensional architecture of structured RNAs. While internal basepairs in a canonical helix stack on both sides, the ends of the helix stack on only one side and are exposed to the loop side, thus ...
Jung C Lee, Robin R Gutell
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VfoldCPX Server: Predicting RNA-RNA Complex Structure and Stability. [PDF]
PLoS ONE, 2016 RNA-RNA interactions are essential for genomic RNA dimerization, mRNA splicing, and many RNA-related gene expression and regulation processes. The prediction of the structure and folding stability of RNA-RNA complexes is a problem of significant ...
Xiaojun Xu, Shi-Jie Chen
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Statistical Physics of RNA-folding [PDF]
, 2002 We discuss the physics of RNA as described by its secondary structure. We examine the static properties of a homogeneous RNA-model that includes pairing and base stacking energies as well as entropic costs for internal loops.
Mueller, M.
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RNA Thermodynamic Structural Entropy
PLOS ONE, 2015 Conformational entropy for atomic-level, three dimensional biomolecules is known experimentally to play an important role in protein-ligand discrimination, yet reliable computation of entropy remains a difficult problem. Here we describe the first two accurate and efficient algorithms to compute the conformational entropy for RNA secondary structures ...
Juan Antonio Garcia-Martin, Peter Clote
openaire +5 more sources
Cell Reports, 2019 Summary: MicroRNA (miRNA) processing begins with Drosha cleavage, the fidelity of which is critical for downstream processing and mature miRNA target specificity.
Xavier Bofill-De Ros +11 more
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RNA structure determination: From 2D to 3D
Fundamental Research, 2023 RNA molecules serve a wide range of functions that are closely linked to their structures. The basic structural units of RNA consist of single- and double-stranded regions.
Jie Deng +8 more
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