Results 31 to 40 of about 8,924,942 (310)
Fundamental Research, 2022 To enable diverse functions and precise regulation, an RNA sequence often folds into complex yet distinct structures in different cellular states. Probing RNA in its native environment is essential to uncovering RNA structures of biological contexts ...
Meiling Piao +12 more
doaj +1 more source
Detection of genome-scale ordered RNA structure (GORS) in genomes of positive-stranded RNA viruses:Implications for virus evolution and host persistence [PDF]
, 2004 Discrete RNA secondary and higher-order structures, typically local in extent, play a fundamental role in RNA virus replication. Using new bioinformatics analysis methods, we have identified genome-scale ordered RNA structure (GORS) in many genera and ...
Evans, David J +6 more
core +1 more source
BMC Bioinformatics, 2021 Background The functions of RNA molecules are mainly determined by their secondary structures. These functions can also be predicted using bioinformatic tools that enable the alignment of multiple RNAs to determine functional domains and/or classify RNA ...
Tomasz Woźniak +3 more
doaj +1 more source
Counting RNA Pseudoknotted Structures [PDF]
Journal of Computational Biology, 2011 Abstract In 2004, Condon and coauthors gave a hierarchical classification of exact RNA structure prediction algorithms according to the generality of structure classes that they handle. We complete this classification by adding two recent prediction algorithms. More importantly, we precisely quantify the hierarchy
Saule, Cédric +3 more
openaire +4 more sources
Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs [PDF]
, 2010 Theis C, Janssen S, Giegerich R. Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs. In: Moulton V, Singh M, eds. Algorithms in Bioinformatics. 10th international workshop (WABI 2010), proceedings. Lecture Notes in Bioinformatics. Vol
Corinna Theis +7 more
core +1 more source
Structural 3D Domain Reconstruction of the RNA Genome from Viruses with Secondary Structure Models
Viruses, 2021 Three-dimensional RNA domain reconstruction is important for the assembly, disassembly and delivery functionalities of a packed proteinaceus capsid. However, to date, the self-association of RNA molecules is still an open problem. Recent chemical probing
Simón Poblete, Horacio V. Guzman
doaj +1 more source
Shapes of RNA Pseudoknot Structures [PDF]
Journal of Computational Biology, 2010 Abstract In this article, we study abstract shapes of k -noncrossing, σ -canonical RNA pseudoknot structures.
Christian M. Reidys, Rita R. Wang
openaire +4 more sources
RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure [PDF]
, 2013 Selective gene silencing by RNA interference (RNAi) involves double-stranded small interfering RNA (ds siRNA) composed of single-stranded (ss) guide and passenger RNAs.
Jo Milner +4 more
core +1 more source
Deep Learning in RNA Structure Studies
Frontiers in Molecular Biosciences, 2022 Deep learning, or artificial neural networks, is a type of machine learning algorithm that can decipher underlying relationships from large volumes of data and has been successfully applied to solve structural biology questions, such as RNA structure ...
Haopeng Yu, Yiman Qi, Yiliang Ding
doaj +1 more source
On Topological RNA Interaction Structures [PDF]
Journal of Computational Biology, 2013 Abstract Recently a folding algorithm of topological RNA pseudoknot structures was presented in Reidys et al. ( 2011 ). This algorithm folds single-stranded γ -structures, that is, RNA structures composed by distinct motifs of bounded ...
Jing Qin 0006, Christian M. Reidys
openaire +4 more sources