Results 11 to 20 of about 8,924,942 (310)
RNA Biology, 2022 RNA translation is the rate-limiting step when cells synthesize proteins. Elevating translation efficiency (TE) is intuitively beneficial. Particularly, when viruses invade host cells, how to compete with endogenous RNAs for efficient translation is a ...
Lin Zhu +4 more
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Unveiling RNA structure-mediated regulations of RNA stability in wheat [PDF]
Nature CommunicationsDespite the critical role of mRNA stability in post-transcriptional gene regulation, research on this topic in wheat, a vital agricultural crop, remains unclear. Our study investigated the mRNA decay landscape of durum wheat (Triticum turgidum L.
Haidan Wu +10 more
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Topology of RNA-RNA Interaction Structures [PDF]
Journal of Computational Biology, 2012 40 pages 15 ...
Jørgen E. Andersen +3 more
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Alternate RNA Structures [PDF]
Cold Spring Harbor Perspectives in Biology, 2020 RNA molecules fold into complex three-dimensional structures that sample alternate conformations ranging from minor differences in tertiary structure dynamics to major differences in secondary structure. This allows them to form entirely different substructures with each population potentially giving rise to a distinct biological outcome.
Marie Teng-Pei, Wu, Victoria, D'Souza
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Irreducibility in RNA Structures [PDF]
Bulletin of Mathematical Biology, 2009 In this paper we study irreducibility in RNA structures. By RNA structure we mean RNA secondary as well as RNA pseudoknot structures. In our analysis we shall contrast random and minimum free energy (mfe) configurations. We compute various distributions: of the numbers of irreducible substructures, their locations and sizes, parameterized in terms of ...
Jin, Emma Y., Reidys, Christian M.
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Deconstructing internal ribosome entry site elements: an update of structural motifs and functional divergences [PDF]
Open Biology, 2018 Beyond the general cap-dependent translation initiation, eukaryotic organisms use alternative mechanisms to initiate protein synthesis. Internal ribosome entry site (IRES) elements are cis-acting RNA regions that promote internal initiation of ...
Gloria Lozano +2 more
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Alignments of RNA Structures [PDF]
IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2010 We describe a theoretical unifying framework to express the comparison of RNA structures, which we call alignment hierarchy. This framework relies on the definition of common supersequences for arc-annotated sequences and encompasses the main existing models for RNA structure comparison based on trees and arc-annotated sequences with a variety of edit ...
Blin, Guillaume +4 more
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Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
, 2010 For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
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RNA packaging and uncoating in simple single-stranded RNA viruses [PDF]
, 2012 Simple (non-enveloped) small, positive-sense single-stranded RNA viruses infect hosts from all kingdoms of life. However, their assembly and uncoating processes remain poorly understood. For turnip crinkle virus (TCV), 3D reconstructions by cryoelectron
Bakker, Saskia
core +5 more sources
Flexible pri-miRNA structures enable tunable production of 5’ isomiRs
RNA Biology, 2022 The Drosha cleavage of a pri-miRNA defines mature microRNA sequence. Drosha cleavage at alternative positions generates 5’ isoforms (isomiRs) which have distinctive functions. To understand how pri-miRNA structures influence Drosha cleavage, we performed
Xavier Bofill-De Ros +6 more
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