Results 11 to 20 of about 1,628,380 (301)

Structural and dynamic mechanisms for coupled folding and tRNA recognition of a translational T-box riboswitch

open access: yesNature Communications, 2023
T-box riboswitches are unique riboregulators where gene regulation is mediated through interactions between two highly structured RNAs. Despite extensive structural insights, how RNA-RNA interactions drive the folding and structural transitions of T-box ...
Xiaolin Niu   +5 more
doaj   +1 more source

Canonical RNA Pseudoknot Structures [PDF]

open access: yesJournal of Computational Biology, 2008
21 pages,7 ...
Ma, Gang, Reidys, Christian M.
openaire   +3 more sources

High-resolution NMR structure of an RNA model system : the 14-mer cUUCGg tetraloop hairpin RNA [PDF]

open access: yes, 2010
We present a high-resolution nuclear magnetic resonance (NMR) solution structure of a 14-mer RNA hairpin capped by cUUCGg tetraloop. This short and very stable RNA presents an important model system for the study of RNA structure and dynamics using NMR ...
Nozinovic, Senada   +4 more
core   +2 more sources

SS/SW BASE PAIRS ARE THE ONLY BASE PAIRS INVOLVED IN LONG-RANGE RNA TERTIARY MOTIFS

open access: yesJournal of Bioinformatics and Genomics, 2020
The structure of noncoding RNAs largely determines their functions. With the rapid growth of experimental data on the RNA secondary structures, the task of predicting its spatial structure becomes the most urgent task of RNA bioinformatics.
Manakov, A.K.   +2 more
doaj   +1 more source

Recent Advances in Targeted Nanocarriers for the Management of Triple Negative Breast Cancer

open access: yesPharmaceutics, 2023
Triple-negative breast cancer (TNBC) is a life-threatening form of breast cancer which has been found to account for 15% of all the subtypes of breast cancer.
Rajesh Pradhan   +5 more
doaj   +1 more source

Cooperativity and Interdependency between RNA Structure and RNA–RNA Interactions

open access: yesNon-Coding RNA, 2021
Complex RNA–RNA interactions are increasingly known to play key roles in numerous biological processes from gene expression control to ribonucleoprotein granule formation.
Ilias Skeparnias, Jinwei Zhang
doaj   +1 more source

RNA STRUCTURAL SEGMENTATION [PDF]

open access: yes, 2009
We describe several dynamic programming segmentation algorithms to segment RNA secondary and tertiary structures into distinct domains. For this purpose, we consider fitness functions that variously depend on (i) base pairing probabilities in the Boltzmann low energy ensemble of structures, (ii) contact maps inferred from 3-dimensional structures, and (
Ivan, Dotú   +3 more
openaire   +2 more sources

An RNA Thermometer Activity of the West Nile Virus Genomic 3′-Terminal Stem-Loop Element Modulates Viral Replication Efficiency during Host Switching

open access: yesViruses, 2020
The 3′-terminal stem-loop (3′SL) of the RNA genome of the flavivirus West Nile (WNV) harbors, in its stem, one of the sequence elements that are required for genome cyclization.
Alexandra Meyer   +7 more
doaj   +1 more source

RNA structure

open access: yesCurrent Opinion in Structural Biology, 1998
New information concerning RNA structure is accumulating at an ever increasing rate-from short helices with mismatched bases of 5S rRNA and complex RNA aptamers. The importance of recurring structural motifs, ion binding, and the kinetics and energetics of folding in RNA structure and function is now being recognized and addressed.
Conn, Graeme L., Draper, David E.
openaire   +3 more sources

An ultra low-input method for global RNA structure probing uncovers Regnase-1-mediated regulation in macrophages

open access: yesFundamental Research, 2022
To enable diverse functions and precise regulation, an RNA sequence often folds into complex yet distinct structures in different cellular states. Probing RNA in its native environment is essential to uncovering RNA structures of biological contexts ...
Meiling Piao   +12 more
doaj   +1 more source

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