Results 41 to 50 of about 1,628,380 (301)

VfoldCPX Server: Predicting RNA-RNA Complex Structure and Stability. [PDF]

open access: yesPLoS ONE, 2016
RNA-RNA interactions are essential for genomic RNA dimerization, mRNA splicing, and many RNA-related gene expression and regulation processes. The prediction of the structure and folding stability of RNA-RNA complexes is a problem of significant ...
Xiaojun Xu, Shi-Jie Chen
doaj   +1 more source

New insights into the biological role of mammalian ADARs; the RNA editing proteins [PDF]

open access: yes, 2015
The ADAR proteins deaminate adenosine to inosine in double-stranded RNA which is one of the most abundant modifications present in mammalian RNA.
Arieti, Fabiana   +4 more
core   +2 more sources

RNA secondary structure design [PDF]

open access: yesPhysical Review E, 2007
11 pages, 10 ...
Burghardt, Bernd, Hartmann, Alexander K.
openaire   +4 more sources

RNA structure prediction: progress and perspective

open access: yes, 2014
Many recent exciting discoveries have revealed the versatility of RNAs and their importance in a variety of cellular functions which are strongly coupled to RNA structures.
Shi, Ya-Zhou   +3 more
core   +1 more source

RNA structure determination: From 2D to 3D

open access: yesFundamental Research, 2023
RNA molecules serve a wide range of functions that are closely linked to their structures. The basic structural units of RNA consist of single- and double-stranded regions.
Jie Deng   +8 more
doaj   +1 more source

Alignments of RNA Structures [PDF]

open access: yesIEEE/ACM Transactions on Computational Biology and Bioinformatics, 2010
We describe a theoretical unifying framework to express the comparison of RNA structures, which we call alignment hierarchy. This framework relies on the definition of common supersequences for arc-annotated sequences and encompasses the main existing models for RNA structure comparison based on trees and arc-annotated sequences with a variety of edit ...
Blin, Guillaume   +4 more
openaire   +4 more sources

Statistical Physics of RNA-folding [PDF]

open access: yes, 2002
We discuss the physics of RNA as described by its secondary structure. We examine the static properties of a homogeneous RNA-model that includes pairing and base stacking energies as well as entropic costs for internal loops.
Mueller, M.
core   +2 more sources

A normal genetic variation modulates synaptic MMP‐9 protein levels and the severity of schizophrenia symptoms

open access: yesEMBO Molecular Medicine, 2017
Matrix metalloproteinase 9 (MMP‐9) has recently emerged as a molecule that contributes to pathological synaptic plasticity in schizophrenia, but explanation of the underlying mechanisms has been missing.
Katarzyna Lepeta   +10 more
doaj   +1 more source

Probing RNA recognition by human ADAR2 using a high-throughput mutagenesis method. [PDF]

open access: yes, 2016
Adenosine deamination is one of the most prevalent post-transcriptional modifications in mRNA. In humans, ADAR1 and ADAR2 catalyze this modification and their malfunction correlates with disease. Recently our laboratory reported crystal structures of the
Beal, Peter A, Wang, Yuru
core   +1 more source

A comparative analysis of mRNA enrichment strategies and guidance for improving their efficiency

open access: yesScientific Reports
The pervasive presence of ribosomal RNA (rRNA) in total RNA poses a considerable challenge to the accurate analysis of cellular transcriptomes. In this study, we comprehensively analyze strategies for Saccharomyces cerevisiae mRNA enrichment, aiming to ...
Angelika Andrzejewska-Romanowska   +3 more
doaj   +1 more source

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