Results 51 to 60 of about 8,924,942 (310)
Structure of an Archaeal RNA Polymerase [PDF]
Journal of Molecular Biology, 2008 Related multisubunit RNA polymerases (RNAPs) carry out gene transcription in all kingdoms of life. Since structural information is limited to bacterial and eukaryotic RNAPs, we determined the cryo-electron microscopic structure of the RNAP from the thermophilic archaeon Pyrococcus furiosus at 13 A resolution.
Kusser, Anselm G. +6 more
openaire +4 more sources
Structural Alignment of Pseudoknotted RNA [PDF]
Journal of Computational Biology, 2006 In this paper, we address the problem of discovering novel non-coding RNA (ncRNA) using primary sequence, and secondary structure conservation, focusing on ncRNA families with pseudoknotted structures. Our main technical result is an efficient algorithm for computing an optimum structural alignment of an RNA sequence against a genomic substring.
Buhm Han +3 more
openaire +6 more sources
, 2004 Giegerich R, Voss B, Rehmsmeier M. Abstract shapes of RNA. Nucleic Acids Research. 2004;32(16):4843-4851.The function of a non-protein-coding RNA is often determined by its structure.
Rehmsmeier, Marc +3 more
core +1 more source
Cell Reports, 2019 Summary: MicroRNA (miRNA) processing begins with Drosha cleavage, the fidelity of which is critical for downstream processing and mature miRNA target specificity.
Xavier Bofill-De Ros +11 more
doaj +1 more source
RNA Secondary Structure Prediction [PDF]
Current Protocols in Nucleic Acid Chemistry, 2000 AbstractDetails for predicting secondary structure of RNA sequences using free energy minimization are given. Protocols present the use of the RNAstructure computer program (for PCs) and the mfold server (for Unix platforms). The minimum free energy structure and a set of suboptimal structures with similar free energies are predicted.
Mathews, David H. +2 more
openaire +5 more sources
Interplay of 'induced fit' and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch [PDF]
, 2006 Riboswitches are highly structured elements in the 50-untranslated regions (50-UTRs) of messenger RNA that control gene expression by specifically binding to small metabolite molecules. They consist of an aptamer domain responsible for ligand binding and
Wöhnert, Jens +5 more
core +1 more source
Helix capping in RNA structure. [PDF]
PLoS ONE, 2014 Helices are an essential element in defining the three-dimensional architecture of structured RNAs. While internal basepairs in a canonical helix stack on both sides, the ends of the helix stack on only one side and are exposed to the loop side, thus ...
Jung C Lee, Robin R Gutell
doaj +1 more source
Structure of the Complete RNA Polymerase II Elongation Complex and its Interaction with the Elongation Factor TFIIS [PDF]
, 2005 This thesis describes crystal structures of complete, 12-subunit yeast RNA polymerase II (Pol II) in complex with a synthetic transcription bubble and product RNA, with an NTP substrate analogue, and in complex with the transcription elongation factor ...
Kettenberger, Hubert
core +1 more source
Domain orientation in the RNA helicase YxiN and the role of conformational changes for RNA unwinding [PDF]
, 2010 The RNA helicase YxiN from Bacillus subtilis is a member of the family of DEAD box proteins. YxiN is able to unwind RNA double strands in an ATP-dependent manner. The ability to catalyse RNA rearrangement is in vivo presumably necessary for the bacterial
Karow, Anne R.
core +1 more source
VfoldCPX Server: Predicting RNA-RNA Complex Structure and Stability. [PDF]
PLoS ONE, 2016 RNA-RNA interactions are essential for genomic RNA dimerization, mRNA splicing, and many RNA-related gene expression and regulation processes. The prediction of the structure and folding stability of RNA-RNA complexes is a problem of significant ...
Xiaojun Xu, Shi-Jie Chen
doaj +1 more source